Noninvasive detection of epicardial and endocardial activity of the heart. 2011

T F Oostendorp, and P F H M van Dessel, and R Coronel, and C Belterman, and A C Linnenbank, and I H van Schie, and A van Oosterom, and P Oosterhoff, and P M van Dam, and J M T de Bakker
The Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Radboud University Nijmegen, Nijmegen, the Netherlands.

Determining electrical activation of the heart in a noninvasive way is one of the challenges in cardiac electrophysiology. The ECG provides some, but limited information about the electrical status of the heart. This article describes a method to determine both endocardial and epicardial activation of the heart of an individual patient from 64 electrograms recorded from the body surface. Information obtained in this way might be helpful for the treatment of arrhythmias, to assess the effect of drugs on conduction in the heart and to assess electrical stability of the heart.

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