Increased resting metabolic rate in girls with Rett syndrome compared to girls with developmental disabilities. 2011

P Platte, and H Jaschke, and C Herbert, and G C Korenke
Department of Psychology, Biological Psychology, Clinical Psychology and Psychotherapy, University of Würzburg,Würzburg, Germany. platte@psychologie.uni- wuerzburg.de

The aim of this study was to determine the body composition and resting metabolic rate (RMR) of girls with Rett syndrome (RS) (n=15) and to compare them with an equally handicapped group of girls with developmental disabilities (DD) (n=13). Body composition was measured by bioelectrical impedance analysis and RMR  -  the amount of energy expended while at rest  -  by indirect calorimetry. Weight, height, body mass index (BMI), BMI percentiles and food intake were all measured and calculated by standardized procedures. Feeding time, ambulatory status and ability to self-feed were also assessed. Due to the sampling, there were no significant differences in age, height, weight, BMI, BMI percentiles and ambulatory status. Significant differences between groups were found for lower percentage lean body mass (LBM) (64.2±14.6 vs. 84.4±24.6) and higher absolute and relative fat mass (FM) in RS. RMR values adjusted for LBM were significantly higher in the group of girls with RS (approximately 160 kcal/day), indicating that higher energy expenditure is a component of increased risk of severely low body weight.

UI MeSH Term Description Entries
D001823 Body Composition The relative amounts of various components in the body, such as percentage of body fat. Body Compositions,Composition, Body,Compositions, Body
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D002149 Energy Intake Total number of calories taken in daily whether ingested or by parenteral routes. Caloric Intake,Calorie Intake,Intake, Calorie,Intake, Energy
D002153 Calorimetry, Indirect Calculation of the energy expenditure in the form of heat production of the whole body or individual organs based on respiratory gas exchange. Calorimetry, Respiration,Calorimetries, Indirect,Calorimetries, Respiration,Indirect Calorimetries,Indirect Calorimetry,Respiration Calorimetries,Respiration Calorimetry
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002658 Developmental Disabilities Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed) Child Development Deviations,Child Development Disorders,Child Development Disorders, Specific,Developmental Delay Disorders,Disabilities, Developmental,Development Disorders, Child,Child Development Deviation,Child Development Disorder,Development Deviation, Child,Development Deviations, Child,Development Disorder, Child,Developmental Delay Disorder,Developmental Disability,Deviation, Child Development,Disability, Developmental
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004435 Eating The consumption of edible substances. Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D004734 Energy Metabolism The chemical reactions involved in the production and utilization of various forms of energy in cells. Bioenergetics,Energy Expenditure,Bioenergetic,Energy Expenditures,Energy Metabolisms,Expenditure, Energy,Expenditures, Energy,Metabolism, Energy,Metabolisms, Energy
D005260 Female Females

Related Publications

P Platte, and H Jaschke, and C Herbert, and G C Korenke
February 2003, Journal of the American Dietetic Association,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
August 2003, Nederlands tijdschrift voor geneeskunde,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
April 2006, Journal of pediatric gastroenterology and nutrition,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
July 1997, Obesity research,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
March 1996, Developmental medicine and child neurology,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
January 2004, Disability and rehabilitation,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
December 1992, Clinical genetics,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
August 2023, Scientific reports,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
December 1994, Annals of internal medicine,
P Platte, and H Jaschke, and C Herbert, and G C Korenke
May 1995, Annals of internal medicine,
Copied contents to your clipboard!