Small angle neutron scattering studies of HbA in concentrated solutions. 1990

S Krueger, and S H Chen, and J Hofrichter, and R Nossal
University of Maryland, College Park 20742.

Differential cross-sections for neutrons scattered by normal human hemoglobin have been determined over the range of concentrations from 2 to approximately 35 weight percent. Data are compared with structure factors calculated from models of monodisperse hard spheres interacting through a screened Coulomb potential. Good agreement is noted when the volume fraction eta is adjusted during multivariate fitting of data, but the fitted value of eta is always lower than expected from the known Hb concentration of the samples. Calculations of cross-sections for polydisperse scatterers suggest that the samples may contain oligomers of the fundamental tetrameric Hb molecule.

UI MeSH Term Description Entries
D009502 Neutrons Electrically neutral elementary particles found in all atomic nuclei except light hydrogen; the mass is equal to that of the proton and electron combined and they are unstable when isolated from the nucleus, undergoing beta decay. Slow, thermal, epithermal, and fast neutrons refer to the energy levels with which the neutrons are ejected from heavier nuclei during their decay. Neutron
D011487 Protein Conformation The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain). Conformation, Protein,Conformations, Protein,Protein Conformations
D002263 Carboxyhemoglobin Carbomonoxyhemoglobin,Carbonmonoxyhemoglobin,Carbonylhemoglobin,Carboxyhemoglobin A,Carboxyhemoglobin C
D006441 Hemoglobin A Normal adult human hemoglobin. The globin moiety consists of two alpha and two beta chains.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012542 Scattering, Radiation The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Radiation Scattering,Radiation Scatterings,Scatterings, Radiation

Related Publications

S Krueger, and S H Chen, and J Hofrichter, and R Nossal
July 1988, Biopolymers,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
June 1991, Physical review. A, Atomic, molecular, and optical physics,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
March 2005, Langmuir : the ACS journal of surfaces and colloids,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
February 2003, The European physical journal. E, Soft matter,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
August 2012, Langmuir : the ACS journal of surfaces and colloids,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
February 2007, The journal of physical chemistry. B,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
January 1983, Annual review of biophysics and bioengineering,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
May 2002, Physical review. E, Statistical, nonlinear, and soft matter physics,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
December 2004, Physical review. E, Statistical, nonlinear, and soft matter physics,
S Krueger, and S H Chen, and J Hofrichter, and R Nossal
April 2010, Langmuir : the ACS journal of surfaces and colloids,
Copied contents to your clipboard!