-transparent.png){kind=logo}
4-Phenyl-1H-1,5-benzodiazepin-2(3H)-one reacts in the pres-ence of a concentrated aqueous solution of sodium hydroxide and a quaternary ammonium salt (as catalyst) in benzene (phase transfer catalysis) with propargyl bromide, affording the title benzodiazepine derivative, C(18)H(14)N(2)O. In the mol-ecule, the mean plane of the propargyl substituent is almost perpendicular with that of the amide group [dihedral angle = 87.81 (8)°]. In the crystal, the molecules are linked by C-H⋯O and C-H⋯N inter-actions.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
January 2014,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
December 2012,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
January 2013,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
July 2010,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
January 2012,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
November 2008,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
May 2010,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
July 2010,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
May 2011,
Acta crystallographica. Section E, Structure reports online,
Mohamed Loughzail, and
José A Fernandes, and
Abdesselam Baouid, and
Mohamed Essaber, and
José A S Cavaleiro, and
Filipe A Almeida Paz
December 2011,
Acta crystallographica. Section E, Structure reports online,
