BIOMAT Database Logo BIOMAT Database Logo

Synthesis of azines in solid state: reactivity of solid hydrazine with aldehydes and ketones. 2011

Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Department of Chemistry, Sogang University, Seoul 121-742, Korea.

Highly conjugated azines were prepared by solid state grinding of solid hydrazine and carbonyl compounds such as aldehydes and ketones, using a mortar and a pestle. Complete conversion to the azine product is generally achieved at room temperature within 24 h, without using solvents or additives. The solid-state reactions afford azines as the sole products with greater than 97% yield, producing only water and carbon dioxide as waste.

UI MeSH Term Description Entries
D007659 Ketones Organic compounds containing a carbonyl group Ketone
D002384 Catalysis The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction. Catalyses
D006834 Hydrazines Substituted derivatives of hydrazine (formula H2N-NH2). Hydrazide
D000447 Aldehydes Organic compounds containing a carbonyl group in the form -CHO. Aldehyde
D001391 Azo Compounds Organic chemicals where aryl or alkyl groups are joined by two nitrogen atoms through a double bond (R-N Azo Dye,Azo Dyes,Compounds, Azo,Dye, Azo,Dyes, Azo
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D020650 Combinatorial Chemistry Techniques A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale. Chemistry Techniques, Combinatorial,Techniques, Combinatorial Chemistry,Chemistry Technic, Combinatorial,Chemistry Technics, Combinatorial,Chemistry Technique, Combinatorial,Combinatorial Chemistry Technic,Combinatorial Chemistry Technics,Combinatorial Chemistry Technique,Technic, Combinatorial Chemistry,Technics, Combinatorial Chemistry,Technique, Combinatorial Chemistry

Related Publications

Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Polysaccharide Aldehydes and Ketones: Synthesis and Reactivity.
April 2024, Biomacromolecules,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Solid-State Structure of Protonated Ketones and Aldehydes.
December 2017, Angewandte Chemie (International ed. in English),
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
2'-Hydrazine oligonucleotides: synthesis and efficient conjugation with aldehydes.
January 2005, Nucleic acids symposium series (2004),
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Strategy for the synthesis of polymeric supports with hydrazone linkers for solid-phase alkylation of ketones and aldehydes.
January 2005, Journal of combinatorial chemistry,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Synthesis of trifluoroethyl-substituted ketones from aldehydes and cyclohexanones.
September 2011, Angewandte Chemie (International ed. in English),
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Solid-supported odorless reagents for the dithioacetalization of aldehydes and ketones.
February 2014, Organic letters,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Ligand Redox-Controlled Tandem Synthesis of Azines from Aromatic Alcohols and Hydrazine in Air: One-Pot Synthesis of Phthalazine.
August 2018, The Journal of organic chemistry,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Aldehydes and ketones influence reactivity and selectivity in nickel-catalysed Suzuki-Miyaura reactions.
January 2020, Chemical science,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Reactivity of alpha-(benzoyloxy)crotylstannane with aldehydes in liquid phase and on solid support. Synthesis of substituted lactones.
October 2001, The Journal of organic chemistry,
Byeongno Lee, and Kyu Hyung Lee, and Jaeheung Cho, and Wonwoo Nam, and Nam Hwi Hur
Synthesis of β-, γ-, δ-, ..., ω-halogenated ketones and aldehydes.
October 2010, Chemical reviews,
Copied contents to your clipboard!