BIOMAT Database Logo BIOMAT Database Logo

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease. 1990

M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Division of Radiological Sciences, UMDS, Guy's Hospital, London Bridge, UK.

Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009570 Nitriles Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE. Nitrile
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D003287 Contrast Media Substances used to allow enhanced visualization of tissues. Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D005060 Europe The continent north of AFRICA, west of ASIA and east of the ATLANTIC OCEAN. Northern Europe,Southern Europe,Western Europe
D005260 Female Females
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Technetium-99m tetrofosmin imaging in thyroid diseases: comparison with Tc-99m-pertechnetate, thallium-201 and Tc-99m-methoxyisobutylisonitrile scans.
December 1996, European journal of nuclear medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy.
December 1993, European journal of nuclear medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Comparison of thallium-201 and technetium-99m methoxyisobutyl isonitrile.
November 1992, The American journal of cardiology,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Uptake kinetics of technetium-99m-methoxyisobutylisonitrile and thallium-201 in adult rat heart endothelial and fibroblast-like cells in comparison to myocytes.
January 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
[Technetium-99m isonitrile versus thallium 201 in coronary disease].
January 1994, Revista espanola de cardiologia,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Comparison of techniques for thallium-201-technetium-99m parathyroid imaging.
June 1989, The British journal of radiology,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Assessment of myocardial perfusion and viability with technetium-99m methoxyisobutylisonitrile and thallium-201 rest redistribution in chronic coronary artery disease.
November 1995, European journal of nuclear medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Localization of parathyroid enlargement: experience with technetium-99m methoxyisobutylisonitrile and thallium-201 scintigraphy, ultrasonography and computed tomography.
January 1994, European journal of nuclear medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Uptake of technetium-99m-teboroxime in cultured myocardial cells: comparison with thallium-201 and technetium-99m-sestamibi.
February 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
M N Maisey, and A Lowry, and A Bischof-Delaloye, and R Fridrich, and E Inglese, and M N Khalil, and J B van der Schoot
Parathyroid scintigraphy: comparison of technetium-99m methoxyisobutylisonitrile and technetium-99m tetrofosmin studies.
June 1996, European journal of nuclear medicine,
Copied contents to your clipboard!