BIOMAT Database Logo BIOMAT Database Logo

Effect of plasma gangliosides on the growth of Ehrlich ascites tumor. 1990

S Saha, and A Ghosh
Department of Cell Biology, Chittaranjan National Cancer Institute, Calcutta, India.

Total plasma gangliosides of Ehrlich ascites tumor-bearing mice enhanced tumor growth when adoptively transferred with the same tumor cells in mice. However, individual gangliosides acted differently. Out of 6 gangliosides separated from plasma, 2 components enhanced tumor growth, whereas the remaining 4 inhibited tumor growth. Neither of the 2 enhancing components in various combinations with the 4 inhibitory components could restore the enhancing effect. The enhancing effect was restored only when both the enhancing components were mixed with the remaining 4 ganglioside components, i.e., with full/complete reconstitution.

UI MeSH Term Description Entries
D008297 Male Males
D002286 Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. Ehrlich Ascites Tumor,Ascites Tumor, Ehrlich,Ehrlich Tumor Carcinoma,Tumor, Ehrlich Ascites
D002471 Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. Neoplastic Transformation, Cell,Neoplastic Cell Transformation,Transformation, Neoplastic Cell,Tumorigenic Transformation,Cell Neoplastic Transformation,Cell Neoplastic Transformations,Cell Transformations, Neoplastic,Neoplastic Cell Transformations,Neoplastic Transformations, Cell,Transformation, Cell Neoplastic,Transformation, Tumorigenic,Transformations, Cell Neoplastic,Transformations, Neoplastic Cell,Transformations, Tumorigenic,Tumorigenic Transformations
D002855 Chromatography, Thin Layer Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Chromatography, Thin-Layer,Thin Layer Chromatography,Chromatographies, Thin Layer,Chromatographies, Thin-Layer,Thin Layer Chromatographies,Thin-Layer Chromatographies,Thin-Layer Chromatography
D005732 Gangliosides A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997) Ganglioside,Sialoglycosphingolipids
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D016233 Immunotherapy, Active Active immunization where vaccine is administered for therapeutic or preventive purposes. This can include administration of immunopotentiating agents such as BCG vaccine and Corynebacterium parvum as well as biological response modifiers such as interferons, interleukins, and colony-stimulating factors in order to directly stimulate the immune system. Immune RNA Manipulation,Vaccine Therapy,Active Immunotherapy,Therapy, Vaccine,Active Immunotherapies,Immune RNA Manipulations,Immunotherapies, Active,Manipulation, Immune RNA,Manipulations, Immune RNA,RNA Manipulation, Immune,RNA Manipulations, Immune,Therapies, Vaccine,Vaccine Therapies
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

S Saha, and A Ghosh
Effect of Ehrlich ascites tumor cells on mouse plasma lipoproteins.
January 1971, Zeitschrift fur Krebsforschung,
S Saha, and A Ghosh
[Laser beam effect on the growth of the Ehrlich ascites tumor].
January 1968, Archiv fur Geschwulstforschung,
S Saha, and A Ghosh
Effect of hyperthermia on growth of Ehrlich ascites tumor cells.
November 1988, Cancer biochemistry biophysics,
S Saha, and A Ghosh
Growth-promoting effect of acid mucopolysaccharides on Ehrlich ascites tumor.
May 1966, Cancer research,
S Saha, and A Ghosh
[Proceedings: Effect of growth hormone on growth of Ehrlich ascites tumor cells].
March 1974, [Hokkaido igaku zasshi] The Hokkaido journal of medical science,
S Saha, and A Ghosh
Effect of X-irradiation on the growth of the Ehrlich ascites tumor.
June 1955, Journal of the National Cancer Institute,
S Saha, and A Ghosh
Inhibitory effect of hydroxynitrodihydrothymine on the growth of Ehrlich ascites tumor cells.
May 1978, Cancer treatment reports,
S Saha, and A Ghosh
Effect of urease injections on Ehrlich ascites tumor growth in mice.
January 1972, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
S Saha, and A Ghosh
Effect of hydrocortisone on Ehrlich ascites tumor.
November 1962, Cancer research,
S Saha, and A Ghosh
The effect of recombinant human tumor necrosis factor-alpha on Ehrlich ascites tumor growth.
January 2002, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer,
Copied contents to your clipboard!