Biomaterial Database

Morphological investigations of fibrogenic action of Estonian oil shale dust. 1979

V A Küng

A review of morphological investigations carried out to clarify the pathogenicity of industrial dust produced in the mining and processing of Estonian oil shale is given. Histological examination of lungs of workers in the oil shale industry taken at necropsies showed that the inhalation of oil shale dust over a long period (more than 20 years) may cause the development of occupational pneumoconiotic changes in oil shale miners. The pneumoconiotic process develops slowly and is characterized by changes typical of the interstitial form of pneumoconiotic fibrosis in the lungs. Emphysematous changes and chronic bronchitis also occur. The average chemical content of oil shale as well as of samples of oil shale dust generated during mining and sorting procedures is given. The results of experiments in white rats are presented; these studies also indicate a mild fibrogenic action of Estonian oil shale dust.

UI	MeSH Term	Description	Entries
D008906	Mining	The process of extracting mineral deposits from the earth.
D009784	Occupational Diseases	Diseases caused by factors involved in one's employment.	Diseases, Occupational,Occupational Illnesses,Disease, Occupational,Illnesse, Occupational,Illnesses, Occupational,Occupational Disease,Occupational Illnesse
D010578	Petroleum	Naturally occurring complex liquid hydrocarbons which, after distillation, yield combustible fuels, petrochemicals, and lubricants.	Crude Oil,Crude Oils,Oil, Crude,Oils, Crude,Petroleums
D011009	Pneumoconiosis	A diffuse parenchymal lung disease caused by inhalation of dust and by tissue reaction to their presence. These inorganic, organic, particulate, or vaporized matters usually are inhaled by workers in their occupational environment, leading to the various forms (ASBESTOSIS; BYSSINOSIS; and others). Similar air pollution can also have deleterious effects on the general population.	Bagassosis,Pneumoconioses
D011658	Pulmonary Fibrosis	A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.	Alveolitis, Fibrosing,Idiopathic Diffuse Interstitial Pulmonary Fibrosis,Fibroses, Pulmonary,Fibrosis, Pulmonary,Pulmonary Fibroses,Alveolitides, Fibrosing,Fibrosing Alveolitides,Fibrosing Alveolitis
D004391	Dust	Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed)	House Dust,Housedust,Dust, House
D004957	Estonia	A country in Eastern Europe, bordering the Baltic Sea and Gulf of Finland, between Latvia and Russia. The capital is Tallinn.
D005648	Fuel Oils	Complex petroleum hydrocarbons consisting mainly of residues from crude oil distillation. These liquid products include heating oils, stove oils, and furnace oils and are burned to generate energy.	Fuel Oil,Oil, Fuel,Oils, Fuel
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia