-transparent.png){kind=logo}
The c-fms proto-oncogene product, which is the receptor for the macrophage colony-stimulating factor CSF-1, is always found expressed in acute myeloid leukemia cells, irrespective of their stage of differentiation according to the FAB classification (Dubreuil P, Torrès H, Courcoul M, Birg F, Mannoni P. Blood 1988;72:1081-1085). We have extended this study and looked for c-fms expression in poorly differentiated myeloid leukemias, in a series of acute leukemias of either T or B origin and in biphenotypic leukemias. We now report that expression of c-fms is still related to the myeloid origin of the leukemic proliferation, but that it can also be found in some acute leukemias presenting clonal rearrangements of the T cell receptor gene. Thus expression of the c-fms/CSF-1 receptor may not be exclusively a marker for myeloid proliferations.
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 1991,
Pathobiology : journal of immunopathology, molecular and cellular biology,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 1989,
Haematology and blood transfusion,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 2003,
Leukemia,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
September 1991,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 1981,
Blood cells,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 2010,
Asian Pacific journal of cancer prevention : APJCP,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
November 1992,
Blood,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
November 2003,
British journal of haematology,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 2001,
Cell biochemistry and biophysics,
H Torrès, and
P Dubreuil, and
F Falzetti, and
M A Courcoul, and
M Lopez, and
F Falcinelli, and
F Birg, and
A Tabilio, and
P Mannoni
January 1990,
Growth factors (Chur, Switzerland),
