Biomaterial Database

Isolated abducens nerve palsy secondary to Lemierre syndrome. 2011

Simon R Bababeygy, and Hashem Almarzouki, and Angela N Buffenn

Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Lemierre syndrome is characterized by pharyngotonsillitis that is typically secondary to Fusobacterium necrophorum infection and causes adjacent septic thrombophlebitis and thrombosis with subsequent metastatic abscesses. A 3-year-old boy presented with fever, tonsillar enlargement, and bilateral otomastoiditis with purulent discharge. Physical examination revealed abducens nerve palsy on the left side, with a compensatory left head turn. Otomastoid discharge culture was positive for anaerobic F. necrophorum. Magnetic resonance venography of the head and neck revealed thromboses in left internal jugular vein, left cavernous sinus, left superior ophthalmic vein, and left sigmoid sinus. The patient was treated with anticoagulation and a 10-week course of intravenous antibiotics, including ceftriaxone and metronidazole.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005674	Fusobacterium Infections	Infections with bacteria of the genus FUSOBACTERIUM.	Necrobacillosis,Sphaerophorus Infections,Infections, Fusobacterium,Infections, Sphaerophorus,Fusobacterium Infection,Infection, Fusobacterium,Infection, Sphaerophorus,Necrobacilloses,Sphaerophorus Infection
D005675	Fusobacterium necrophorum	A species of gram-negative, non-spore-forming bacteria isolated from the natural cavities of man and other animals and from necrotic lesions, abscesses, and blood.	Sphaerophorus necrophorus
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000900	Anti-Bacterial Agents	Substances that inhibit the growth or reproduction of BACTERIA.	Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D000925	Anticoagulants	Agents that prevent BLOOD CLOTTING.	Anticoagulant Agent,Anticoagulant Drug,Anticoagulant,Anticoagulant Agents,Anticoagulant Drugs,Anticoagulation Agents,Indirect Thrombin Inhibitors,Agent, Anticoagulant,Agents, Anticoagulant,Agents, Anticoagulation,Drug, Anticoagulant,Drugs, Anticoagulant,Inhibitors, Indirect Thrombin,Thrombin Inhibitors, Indirect
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D057831	Lemierre Syndrome	A superinfection of the damaged oropharyngeal mucosa by FUSOBACTERIUM NECROPHORUM leading to the secondary septic THROMBOPHLEBITIS of the internal jugular vein.	Lemierre Disease,Lemierre's Disease,Lemierre's Syndrome,Postanginal Sepsis,Disease, Lemierre,Disease, Lemierre's,Lemierres Disease,Lemierres Syndrome,Postanginal Sepses,Sepses, Postanginal,Sepsis, Postanginal,Syndrome, Lemierre,Syndrome, Lemierre's
D020434	Abducens Nerve Diseases	Diseases of the sixth cranial (abducens) nerve or its nucleus in the pons. The nerve may be injured along its course in the pons, intracranially as it travels along the base of the brain, in the cavernous sinus, or at the level of superior orbital fissure or orbit. Dysfunction of the nerve causes lateral rectus muscle weakness, resulting in horizontal diplopia that is maximal when the affected eye is abducted and ESOTROPIA. Common conditions associated with nerve injury include INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; ISCHEMIA; and INFRATENTORIAL NEOPLASMS.	Abducens Palsy, Childhood, Benign Recurrent,Cranial Nerve VI Diseases,Lateral Rectus Palsy,Sixth Cranial Nerve Disorders,6th Nerve Palsy,Abducens Nerve Palsy,Abducens Palsy,Benign Recurrent Abducens Palsy of Childhood,Benign Recurrent Abducens Palsy, Children,Cranial Nerve VI Palsy,Sixth Cranial Nerve Diseases,Sixth Cranial Nerve Palsy,Sixth Nerve Palsy,VI Nerve Palsy,VIth Cranial Nerve Diseases,6th Nerve Palsies,Abducens Nerve Disease,Abducens Nerve Palsies,Abducens Palsies,Lateral Rectus Palsies,Palsies, 6th Nerve,Palsies, Abducens,Palsies, Abducens Nerve,Palsies, Lateral Rectus,Palsies, Sixth Nerve,Palsies, VI Nerve,Palsy, 6th Nerve,Palsy, Abducens,Palsy, Abducens Nerve,Palsy, Lateral Rectus,Palsy, Sixth Nerve,Palsy, VI Nerve,Sixth Nerve Palsies