-transparent.png){kind=logo}
Permanent in vitro growing leukemic cell lines have been established from all types of immunologically classified childhood leukemias. Essential characteristics of primary blasts and cultured cells are identical. In contrast to lymphoblastoid, non-leukemic cell lines, the Epstein-Barr-virus specific nuclear angiten (EBNA) is not detected. Up to now 8 Non-B-non-T cell lines (6 of them were derived from children with acute lymphoblastic leukemia, 2 from patients with chronic myeloid leukemia), 8 T-lines and one B-line have been established. Three Non-B-non-T lines from children with acute lymphoblastic leukemia (KM-3, RU-3, MH-3) and one T-cell line (JM) were cultivated by ourselves. Cultured blasts represent a pure tumor material which can be propagated in large quantities. Leukemic cell lines reveal a new approach for the search after leukemia-associated proteins and represent another possibility for the experimental investigation of the etiology of leukemia.
U Schneider, and
H U Schwenk, and
K H Herzog
January 1976,
Deutsche medizinische Wochenschrift (1946),
U Schneider, and
H U Schwenk, and
K H Herzog
August 1973,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
U Schneider, and
H U Schwenk, and
K H Herzog
August 1976,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
U Schneider, and
H U Schwenk, and
K H Herzog
March 1976,
Aktuelle Gerontologie,
U Schneider, and
H U Schwenk, and
K H Herzog
May 1979,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
U Schneider, and
H U Schwenk, and
K H Herzog
August 1981,
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde,
U Schneider, and
H U Schwenk, and
K H Herzog
February 1979,
Klinische Wochenschrift,
U Schneider, and
H U Schwenk, and
K H Herzog
March 1979,
Klinische Wochenschrift,
U Schneider, and
H U Schwenk, and
K H Herzog
January 1977,
Klinische Padiatrie,
U Schneider, and
H U Schwenk, and
K H Herzog
March 1979,
Deutsche medizinische Wochenschrift (1946),
