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A horse with neurological signs and severe meningoencephalitis caused by Aujeszky's disease is described. The diagnosis was established by immunohistochemistry, DNA-in situ hybridization and serological tests. Aujeszky's disease virus antigen and Aujeszky's disease viral DNA were detected in neurons of the cerebrum. In the serum of the horse antibodies against Aujeszky's disease virus were detected in a virus neutralization test, in a blocking ELISA which specifically detects antibodies against the glycoprotein I (Ig) of the virus, in an indirect double sandwich ELISA and with colloidal gold immunoelectron microscopy which detects antibodies directed against the envelope and nucleocapsid of the virus. Intranasal infection of two points with a high dose of Aujeszky's disease virus caused very wild and transient signs. Although the experimental infection induced virus neutralizing antibodies, it failed to induce gI specific antibodies.
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
January 1990,
The Veterinary record,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
February 1988,
Nihon juigaku zasshi. The Japanese journal of veterinary science,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
August 1973,
Tijdschrift voor diergeneeskunde,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
March 1982,
The Veterinary record,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
December 1986,
Revue scientifique et technique (International Office of Epizootics),
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
December 1989,
Australian veterinary journal,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
January 1982,
The Veterinary record,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
January 1982,
The Veterinary record,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
December 1983,
Uirusu,
T S van den Ingh, and
G J Binkhorst, and
T G Kimman, and
J Vreeswijk, and
J M Pol, and
J T van Oirschot
January 1965,
Bulletin - Office international des epizooties,
