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Persistent infection with Edmonston strain of measles virus was established in a highly susceptible clone of HEp-2 cells. The morphological and cytogenic aspects of persistent infection are presented. Carriage of measles virus in cells persistently infected is marked by important differences between standard Edmonston strain and virus stocks isolated from time to time from the carrier state. It is especially significant that cell fusion capacity decreased in amount concordant with the drop in the yield of infectious virus. Addition of UV inactivated Sendai virus, trypsin treatment or incubation at suboptimal temperatures precipitate the cytocidal effect of measles virus. Some clinical implications of reactivation of the lytic cycle in the carrier state are suggested.
C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
January 1978,
Microbios,
C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
February 1961,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
C Cernescu, and
M Iftimovici, and
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L Popescu, and
O Dumitrescu, and
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L M Popescu
January 1982,
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C Cernescu, and
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L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
January 1962,
Journal of the National Cancer Institute,
C Cernescu, and
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D Rojanski, and
L Popescu, and
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L M Popescu
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September 2004,
Microbial pathogenesis,
C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
December 1962,
Life sciences (1962),
C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
February 2018,
Cellular reprogramming,
C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
October 2001,
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C Cernescu, and
M Iftimovici, and
D Rojanski, and
L Popescu, and
O Dumitrescu, and
S Constantinescu, and
L M Popescu
October 1956,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
