BIOMAT Database Logo BIOMAT Database Logo

Sulfated mucopolysaccharides from normal and virus transformed rodent fibroblasts. 1979

V P Chiarugi, and C P Dietrich

The sulfated mucopolysaccharide composition of normal and virus transformed Balb 3T3 and BHK21 cell lines is reported. It is shown that normal 3T3 cells contain mainly chondroitin sulfate B and heparitin sulfate. Relatively higher amounts of chondroitin sulface AC were observed in polyoma virus transformed 3T3 cells, besides an absolute increase of all the three sulfated mucopolysaccharides in the polyoma and SV 40 transformed cells. It is shown also that the three sulfated mucopolysaccharides are at least in part at the cell surface. Similar differences in sulfated mucopolysaccharide composition of normal and virus transformed BHK cell lines were also observed.

UI MeSH Term Description Entries
D011120 Polyomavirus A genus of potentially oncogenic viruses of the family POLYOMAVIRIDAE. These viruses are normally present in their natural hosts as latent infections. The virus is oncogenic in hosts different from the species of origin. Bovine polyomavirus,Murine polyomavirus,Hamster polyomavirus,Polyoma Virus,Polyoma Viruses,Bovine polyomaviruses,Hamster polyomaviruses,Murine polyomaviruses,Polyomaviruses,Virus, Polyoma,Viruses, Polyoma,polyomavirus, Hamster,polyomaviruses, Bovine,polyomaviruses, Murine
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002472 Cell Transformation, Viral An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. Transformation, Viral Cell,Viral Cell Transformation,Cell Transformations, Viral,Transformations, Viral Cell,Viral Cell Transformations
D004586 Electrophoresis An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current. Electrophoreses
D006025 Glycosaminoglycans Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine (see ACETYLGLUCOSAMINE) or N-acetylgalactosamine (see ACETYLGALACTOSAMINE). Glycosaminoglycan,Mucopolysaccharides
D006224 Cricetinae A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS. Cricetus,Hamsters,Hamster
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001358 Avian Sarcoma Viruses Group of alpharetroviruses (ALPHARETROVIRUS) producing sarcomata and other tumors in chickens and other fowl and also in pigeons, ducks, and RATS. Avian Sarcoma Virus B77,Chicken Sarcoma Virus B77,Chicken Tumor 1 Virus,Fujinami sarcoma virus,Sarcoma Viruses, Avian,Avian Sarcoma Virus,Fujinami sarcoma viruses,Sarcoma Virus, Avian,Virus, Avian Sarcoma,Viruses, Avian Sarcoma,sarcoma virus, Fujinami,virus, Fujinami sarcoma,viruses, Fujinami sarcoma
D013464 Sulfuric Acids Inorganic and organic derivatives of sulfuric acid (H2SO4). The salts and esters of sulfuric acid are known as SULFATES and SULFURIC ACID ESTERS respectively. Acids, Sulfuric
D013539 Simian virus 40 A species of POLYOMAVIRUS originally isolated from Rhesus monkey kidney tissue. It produces malignancy in human and newborn hamster kidney cell cultures. SV40 Virus,Vacuolating Agent,Polyomavirus macacae,SV 40 Virus,SV 40 Viruses,SV40 Viruses,Vacuolating Agents

Related Publications

V P Chiarugi, and C P Dietrich
Differences in the sulfated macromolecules synthesized by normal and transformed hamster fibroblasts.
January 1978, Biochimica et biophysica acta,
V P Chiarugi, and C P Dietrich
The effect of dibutyryl cyclic adenosine monophosphate on synthesis of sulfated acid mucopolysaccharides by transformed fibroblasts.
September 1972, The Journal of biological chemistry,
V P Chiarugi, and C P Dietrich
Membrane glycopeptides from virus-transformed hamster fibroblasts and the normal counterpart.
June 1979, Biochemistry,
V P Chiarugi, and C P Dietrich
35S incorporation into sulfated mucopolysaccharides from embryonic, normal, and neoplastic liver cells.
January 1976, Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology,
V P Chiarugi, and C P Dietrich
Production of mucopolysaccharides by normal and transformed cells.
January 1973, Proceedings of the National Academy of Sciences of the United States of America,
V P Chiarugi, and C P Dietrich
Synthesis of sulfated mucopolysaccharides by chick corneal fibroblasts in vitro.
May 1974, Experimental eye research,
V P Chiarugi, and C P Dietrich
Polyamines in normal and in virus-transformed chick embryo fibroblasts.
July 1974, Cancer research,
V P Chiarugi, and C P Dietrich
Cyclic AMP-binding proteins in normal and virus-transformed fibroblasts.
April 1977, Archives of biochemistry and biophysics,
V P Chiarugi, and C P Dietrich
SURFACE MUCOPOLYSACCHARIDES OF POLYOMA VIRUS TRANSFORMED CELLS.
August 1963, Journal of cellular and comparative physiology,
V P Chiarugi, and C P Dietrich
Isolation of a glucose transport system from normal chicken fibroblasts and from chicken fibroblasts transformed by Rous sarcoma virus.
January 1980, Cold Spring Harbor symposia on quantitative biology,
Copied contents to your clipboard!