-transparent.png){kind=logo}
Markers of hepatitis B virus (HBV) and immune response against them were studied in 18 chronic asymptomatic carriers, 8 patients of the virus induced chronic liver disease (CLD), and 7 patients of chronic alcoholic liver cirrhosis, who were also chronic HBV carriers (CALC). The LMI responses to HBeAg were elevated in HBeAg and/or HBV-DNA positive chronic asymptomatic carriers, (median response 31.5%), along with elevation of serum alanine aminotransferase (sALT) levels (59-150 IU/l). On the other hand the LMI responses to this antigen, in HBeAg and HBV-DNA negative chronic carriers were in the normal range (median response 12%) and their sALT levels were also normal (7-50 IU/l). The CLD and CALC patients did not show any relation between their LMI to HBeAg and sALT levels. In contrast no relation between LMI to HBsAg and sALT levels was observed in any group. The LMI responses to HBsAg in CLD patients were elevated (median response 38%) and the responses of chronic asymptomatic carriers and CALC patients were either in the normal range or poor (median responses, 18 and 7% respectively), irrespective of their sALT levels. These results suggest that T cell responses to both the antigens may be involved in liver cell damage.
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
November 1990,
Journal of immunology (Baltimore, Md. : 1950),
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
December 1993,
American journal of clinical pathology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
April 1981,
Springer seminars in immunopathology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
January 2015,
Caspian journal of internal medicine,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
October 1990,
Gastroenterology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
January 1990,
Springer seminars in immunopathology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
April 1979,
Pathology, research and practice,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
January 1979,
Laboratory investigation; a journal of technical methods and pathology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
August 1979,
Gastroenterology,
V Haridas, and
S Rath, and
V Bal, and
A P Kulkarni, and
S T Plumber, and
S R Naik, and
R S Kamat
October 1989,
Hepato-gastroenterology,
