BIOMAT Database Logo BIOMAT Database Logo

The critical role of the external carotid artery in cerebral perfusion of patients with total occlusion of the internal carotid artery. 2012

I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Department of Vascular Surgery, Attikon University, Hospital, University of Athens, Athens, Greece. dalainas@freemail.gr

OBJECTIVE The ipsilateral external carotid artery (ECA) can potentially provide an important collateral pathway for cerebral blood flow in the presence of occlusion or severe stenosis of the internal carotid artery (ICA), recovering up to 15% of the middle cerebral arterial flow. The aim of the study is to elucidate the role of ECA in cerebral flow of patients with total ICA occlusion. METHODS Retrospective study of prospectively collected data of 139 patients with total ICA occlusions. The patients were divided to symptomatic and asymptomatic and were categorized in four subgroups according to the stenosis rates: A) ipsilateral ECA<70% and contralateral internal carotid artery stenosis <70%; B) ipsilateral ECA stenosis <70% and contralateral internal carotid artery stenosis ≥70%; C) ipsilateral ECA stenosis ≥70% and contralateral ICA stenosis <70%; D) ipsilateral ECA stenosis ≥70% and contralateral ICA stenosis ≥75%. RESULTS Fifty eight (41.7%) patients were asymptomatic. The highest rate (48.2%) of asymptomatic patients was in Group A. Among patients with strokes, the highest rate belonged in groups C and D (44.4% and 50% respectively) where ipsilateral ECA stenosis was ≥70% irrespectively of the contralateral ICA patency. Ipsilateral external carotid artery stenosis ≥70% proved to be and independent risk factor for symptom presentation (P=0.013). CONCLUSIONS The study reveals the significant role of ECA patency in cerebral flow in patients with ICA occlusion.

UI MeSH Term Description Entries
D008297 Male Males
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D002342 Carotid Artery, External Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck. Arteries, External Carotid,Artery, External Carotid,Carotid Arteries, External,External Carotid Arteries,External Carotid Artery
D002343 Carotid Artery, Internal Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose. Arteries, Internal Carotid,Artery, Internal Carotid,Carotid Arteries, Internal,Internal Carotid Arteries,Internal Carotid Artery
D002533 Cerebral Angiography Radiography of the vascular system of the brain after injection of a contrast medium. Angiography, Cerebral,Angiographies, Cerebral,Cerebral Angiographies
D002546 Ischemic Attack, Transient Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6) Brain Stem Ischemia, Transient,Cerebral Ischemia, Transient,Crescendo Transient Ischemic Attacks,Transient Ischemic Attack,Anterior Circulation Transient Ischemic Attack,Brain Stem Transient Ischemic Attack,Brain TIA,Brainstem Ischemia, Transient,Brainstem Transient Ischemic Attack,Carotid Circulation Transient Ischemic Attack,Posterior Circulation Transient Ischemic Attack,TIA (Transient Ischemic Attack),Transient Ischemic Attack, Anterior Circulation,Transient Ischemic Attack, Brain Stem,Transient Ischemic Attack, Brainstem,Transient Ischemic Attack, Carotid Circulation,Transient Ischemic Attack, Posterior Circulation,Transient Ischemic Attack, Vertebrobasilar Circulation,Transient Ischemic Attacks, Crescendo,Vertebrobasilar Circulation Transient Ischemic Attack,Attack, Transient Ischemic,Attacks, Transient Ischemic,Brainstem Ischemias, Transient,Cerebral Ischemias, Transient,Ischemia, Transient Brainstem,Ischemia, Transient Cerebral,Ischemias, Transient Brainstem,Ischemias, Transient Cerebral,Ischemic Attacks, Transient,TIA, Brain,TIAs (Transient Ischemic Attack),Transient Brainstem Ischemia,Transient Cerebral Ischemia,Transient Cerebral Ischemias,Transient Ischemic Attacks
D002560 Cerebrovascular Circulation The circulation of blood through the BLOOD VESSELS of the BRAIN. Brain Blood Flow,Regional Cerebral Blood Flow,Cerebral Blood Flow,Cerebral Circulation,Cerebral Perfusion Pressure,Circulation, Cerebrovascular,Blood Flow, Brain,Blood Flow, Cerebral,Brain Blood Flows,Cerebral Blood Flows,Cerebral Circulations,Cerebral Perfusion Pressures,Circulation, Cerebral,Flow, Brain Blood,Flow, Cerebral Blood,Perfusion Pressure, Cerebral,Pressure, Cerebral Perfusion
D003097 Collateral Circulation Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels. Blood Circulation, Collateral,Circulation, Collateral,Collateral Blood Circulation,Collateral Circulation, Blood,Blood Collateral Circulation,Circulation, Blood Collateral,Circulation, Collateral Blood,Collateral Blood Circulations,Collateral Circulations,Collateral Circulations, Blood

Related Publications

I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Assessment of the contribution of the external carotid artery to brain perfusion in patients with internal carotid artery occlusion.
November 2008, Stroke,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
External carotid endarterectomy in the treatment of symptomatic patients with internal carotid artery occlusion.
October 1988, Annals of vascular surgery,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
External carotid artery stenting in symptomatic internal carotid artery occlusion.
August 2020, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Cerebral cortical microinfarcts in patients with internal carotid artery occlusion.
October 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Evaluation of cerebral perfusion reserve in patients with carotid-artery occlusion.
February 1984, Lancet (London, England),
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Evaluation of cerebral perfusion reserve in patients with carotid-artery occlusion.
January 1984, Lancet (London, England),
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Anterior cerebral artery dilation to increase cerebral perfusion in a patient with chronic internal carotid artery occlusion.
May 2023, Journal of neuroradiology = Journal de neuroradiologie,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
External carotid artery angioplasty and stenting to augment cerebral perfusion in the setting of subacute symptomatic ipsilateral internal carotid artery occlusion. Case report.
December 2007, Journal of neurosurgery,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Quantitative cerebral perfusion MRI and CO2 reactivity measurements in patients with symptomatic internal carotid artery occlusion.
September 2002, NeuroImage,
I Dalainas, and E D Avgerinos, and M E Daskalopoulos, and A Papapetrou, and C P Papasideris, and V Katsikas, and K Xiromeritis, and K Moulakakis, and T Gianakopoulos, and C D Liapis
Collateral role of the external carotid artery and its branches in occlusion of the internal carotid artery.
March 1994, International angiology : a journal of the International Union of Angiology,
Copied contents to your clipboard!