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We have attempted to determine whether amebal viruses are capable of viral conversion of the virulence of Entamoeba histolytical. Amebae of little or no virulence for the newborn hamster liver were infected with viruses obtained from four amebal strains of different virulence. Cultures of surviving amebae were increased in virulence by viruses from amebae of high, moderate, or low virulence, but decreased in virulence by the virus of the second most pathogenic amebal strain. Sequential infection with two viruses did not produce consistent cumulative effects on virulence. The changes in virulence noted are considered to be the unpredictable result of either selection pressures exerted by the lytic virus infection or possibly viral alterations of the amebae.
C F Mattern, and
D B Keister, and
L S Diamond
January 2020,
Frontiers in cellular and infection microbiology,
C F Mattern, and
D B Keister, and
L S Diamond
January 1967,
Veterinary medicine, small animal clinician : VM, SAC,
C F Mattern, and
D B Keister, and
L S Diamond
January 1972,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
C F Mattern, and
D B Keister, and
L S Diamond
January 1956,
Revista brasileira de tuberculose e doencas toracicas,
C F Mattern, and
D B Keister, and
L S Diamond
March 1970,
Gaceta medica de Mexico,
C F Mattern, and
D B Keister, and
L S Diamond
January 1994,
Progress in clinical parasitology,
C F Mattern, and
D B Keister, and
L S Diamond
January 1980,
Annali Sclavo; rivista di microbiologia e di immunologia,
C F Mattern, and
D B Keister, and
L S Diamond
February 1994,
Parasitology today (Personal ed.),
C F Mattern, and
D B Keister, and
L S Diamond
December 2019,
Infection and immunity,
C F Mattern, and
D B Keister, and
L S Diamond
August 1999,
Current opinion in microbiology,
