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Radionuclide studies of left ventricular function in normal subjects. 1990

C G Wathen, and A L Muir, and W J Hannan
Department of Medicine, Royal Infirmary, Edinburgh, UK.

The effects of age and exercise on cardiac function in a normal male population have been assessed by ECG-gated radionuclide ventriculography. Fifty-nine subjects aged from 25 to 54 years were studied (mean 44 +/- 10 S.D. years). Resting left ventricular ejection fraction (LVEF) was 0.54 +/- 0.07 and this increased by 0.07 +/- 0.05 during supine submaximal exercise at 75 watts. The mean increase in cardiac output on exercise was 93 +/- 30%. Stroke volume increased on exercise by 23 +/- 13% and end-systolic volume decreased by 10 +/- 16%. There was a weak correlation (P less than 0.05) between age and change in LVEF on exercise but the increase in cardiac output on exercise was not age dependent. It is important to use an age matched control population in any study of cardiac function.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging
D015444 Exercise Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure. Aerobic Exercise,Exercise, Aerobic,Exercise, Isometric,Exercise, Physical,Isometric Exercise,Physical Activity,Acute Exercise,Exercise Training,Activities, Physical,Activity, Physical,Acute Exercises,Aerobic Exercises,Exercise Trainings,Exercise, Acute,Exercises,Exercises, Acute,Exercises, Aerobic,Exercises, Isometric,Exercises, Physical,Isometric Exercises,Physical Activities,Physical Exercise,Physical Exercises,Training, Exercise,Trainings, Exercise
D015637 Gated Blood-Pool Imaging Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS). Angiography, Gated Radionuclide,Equilibrium Radionuclide Angiography,Equilibrium Radionuclide Ventriculography,Gated Blood-Pool Scintigraphy,Gated Equilibrium Blood-Pool Scintigraphy,Radionuclide Angiography, Gated,Radionuclide Ventriculography, Gated,Scintigraphy, Equilibrium,Ventriculography, Equilibrium Radionuclide,Ventriculography, Gated Radionuclide,Blood-Pool Scintigraphy,Equilibrium Radionuclide Angiocardiography,Gated Equilibrium Blood Pool Scintigraphy,Angiocardiographies, Equilibrium Radionuclide,Angiocardiography, Equilibrium Radionuclide,Angiographies, Equilibrium Radionuclide,Angiographies, Gated Radionuclide,Angiography, Equilibrium Radionuclide,Blood Pool Scintigraphy,Blood-Pool Imaging, Gated,Blood-Pool Imagings, Gated,Blood-Pool Scintigraphies,Blood-Pool Scintigraphies, Gated,Blood-Pool Scintigraphy, Gated,Equilibrium Radionuclide Angiocardiographies,Equilibrium Radionuclide Angiographies,Equilibrium Radionuclide Ventriculographies,Equilibrium Scintigraphies,Equilibrium Scintigraphy,Gated Blood Pool Imaging,Gated Blood Pool Scintigraphy,Gated Blood-Pool Imagings,Gated Blood-Pool Scintigraphies,Gated Radionuclide Angiographies,Gated Radionuclide Angiography,Gated Radionuclide Ventriculographies,Gated Radionuclide Ventriculography,Imaging, Gated Blood-Pool,Imagings, Gated Blood-Pool,Radionuclide Angiocardiographies, Equilibrium,Radionuclide Angiocardiography, Equilibrium,Radionuclide Angiographies, Equilibrium,Radionuclide Angiographies, Gated,Radionuclide Angiography, Equilibrium,Radionuclide Ventriculographies, Equilibrium,Radionuclide Ventriculographies, Gated,Radionuclide Ventriculography, Equilibrium,Scintigraphies, Blood-Pool,Scintigraphies, Equilibrium,Scintigraphies, Gated Blood-Pool,Scintigraphy, Blood-Pool,Scintigraphy, Gated Blood-Pool,Ventriculographies, Equilibrium Radionuclide,Ventriculographies, Gated Radionuclide
D016277 Ventricular Function, Left The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance. Left Ventricular Function,Function, Left Ventricular,Functions, Left Ventricular,Left Ventricular Functions,Ventricular Functions, Left

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