[Retrobulbar irradiation of endocrine ophthalmopathy: a comparison between 10 and 16 Gy total dose]. 1990

T Pfluger, and T Wendt, and N Toroutoglou, and C Pickardt, and R Wuttge
Radiologische Klinik und Poliklinik Innenstadt, Ludwig-Maximilians-Universität München.

Severe Graves' ophthalmopathy has been treated in 44 cases by orbital irradiation. 36 out of 37 patients showed a good response or a suspend of the progressive disease. In 17 out of 33 primary irradiations a dose of 10 Gy and in 16 cases a dose of 16 Gy was applied. Measured by ophthalmopathy-index significant better results have been achieved by a total dose of 16 Gy. Because of recurrence after primary irradiation of 10 Gy a re-irradiation became necessary in 35% of the cases. Primary irradiation of 16 Gy has required no further treatment during the same time of observation. A single series of 16 Gy irradiation has shown better results than two series of 10 Gy irradiation concerning the proptosis and alleviation of symptoms.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D005260 Female Females
D006111 Graves Disease A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy). Basedow's Disease,Exophthalmic Goiter,Goiter, Exophthalmic,Graves' Disease,Basedow Disease,Hyperthyroidism, Autoimmune,Basedows Disease,Disease, Basedow,Disease, Basedow's,Disease, Graves,Disease, Graves',Exophthalmic Goiters,Goiters, Exophthalmic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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