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Using sera from lambs experimentally infected with Mycoplasma ovipneumoniae and Pasteurella haemolytica, the development of a good humoral immune response to M. ovipneumoniae was detected by ELISA. The antibody titres peaked 41 days post-infection and good antibody titres were maintained over the 16-week experimental period. Immunoblotting revealed that antibodies to specific antigens appeared in the sera in a sequential manner, some being seen shortly after infection and others developing only after a substantial time lag. Antibodies were raised against almost all the major antigens detected in one laboratory strain (956/2) and against all antigens previously shown to be conserved in 22 Scottish field isolates of M. ovipneumoniae.
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
January 2006,
Clinical and vaccine immunology : CVI,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
January 1991,
Memorias do Instituto Oswaldo Cruz,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
January 1989,
Archiv fur experimentelle Veterinarmedizin,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
February 1998,
Veterinary parasitology,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
January 1999,
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
July 1976,
Research in veterinary science,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
August 2000,
Diseases of aquatic organisms,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
August 2007,
Parasitology research,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
May 1982,
Veterinary microbiology,
D Thirkell, and
R K Spooner, and
G E Jones, and
W C Russell
January 1998,
Veterinary microbiology,
