Biomaterial Database

PO2 levels in middle ear effusions and middle ear mucosa. 1990

M Takahashi, and H Niwa, and N Yanagita

Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.

We measured PO2 values in mucoid and serous middle ear effusions (M-MEE, S-MEE) and in the middle ear mucosa of patients with otitis media with effusion (OME) and compared these values with those obtained from patients with middle ear barotrauma (MEBT). The mean and S.D. values of PO2 in M-MEE, S-MEE and MEBT effusions were 28.9 +/- 11.3, 31.5 +/- 9.5 and 37.0 +/- 15.4 mmHg, respectively; the mean and S.D. values in mucosa were 27.1 +/- 11.9, 27.0 +/- 13.2 and 32.5 +/- 1.0 mmHg, respectively. In health, PO2 values in middle ear mucosa are regulated by its blood supply, oxygen solubility in blood and the blood-to-cavity partial pressure gradient of the gas. When the Eustachian tube (ET) function is severely impaired, PO2 values in the middle ear air cavity depend on the mucosal condition, though some studies have shown a lack of relationship between ET function and PO2 values. Our results show that PO2 values in MEBT are consistently higher than in OME, suggesting that the attributable factor could be a better ET function in MEBT.

UI	MeSH Term	Description	Entries
D009092	Mucous Membrane	An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.	Lamina Propria,Mucosa,Mucosal Tissue,Muscularis Mucosae,Mucous Membranes,Membrane, Mucous,Membranes, Mucous,Mucosae, Muscularis,Mucosal Tissues,Propria, Lamina,Tissue, Mucosal,Tissues, Mucosal
D010034	Otitis Media with Effusion	Inflammation of the middle ear with a clear pale yellow-colored transudate.	Middle Ear Effusion,Otitis Media, Secretory,Otitis Media, Serous,Ear Effusion, Middle,Ear Effusions, Middle,Effusion, Middle Ear,Effusions, Middle Ear,Middle Ear Effusions,Secretory Otitis Media,Serous Otitis Media
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D004432	Ear, Middle	The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.	Tympanic Cavity,Tympanum,Middle Ear,Cavities, Tympanic,Cavity, Tympanic,Ears, Middle,Middle Ears,Tympanic Cavities,Tympanums
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001469	Barotrauma	Injury following pressure changes; includes injury to the eustachian tube, ear drum, lung and stomach.	Barotraumas