[Cochlear physiology and physiopathology. Recent data]. 1990

R Pujol
INSERM, U 254, Université de Montpellier II, Hôpital St Charles.

Our concept of cochlear physiology has changed so drastically over the last decade that most classical textbooks have become obsolete. This bibliographical inadequacy regarding the functioning of the normal cochlea is particularly disturbing when it comes to addressing patho-physiology problems (hearing loss or tinnitus). What drastic changes have there been, that can justify such need for information updating? These relate primarily to the role of one the two types of sensory cells of the cochlea; i.e., the outer hair cells (or OHC). These cells are endowed with contractile properties and react to tonal impulse by modifying the vibration of the cochlear partition. This "active mechanism" response provokes a localized amplification of the vibration imparting to these classical sensory transducers, or inner hair cells (IHC), their optimal frequency sensitivity and discrimination properties. This new concept alone would suffice to justify our present topic. We chose, however, to insert a general presentation of cochlear physiology, the intent of which is to briefly review the classical data and to analyze in some depth the issues that have drastically changed our knowledge.

UI MeSH Term Description Entries
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D006198 Hair Cells, Auditory Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the COCHLEA. Towards the cochlear apex, the length of hair cell bodies and their apical STEREOCILIA increase, allowing differential responses to various frequencies of sound. Auditory Hair Cells,Cochlear Hair Cells,Auditory Hair Cell,Cell, Cochlear Hair,Cells, Cochlear Hair,Cochlear Hair Cell,Hair Cell, Auditory,Hair Cell, Cochlear,Hair Cells, Cochlear
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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