In the introduction the authors mention the best known authors who investigated the dynamics of interpersonal relations in families with a schizophrenic patient. The illustrative statement of an intelligent loving sister is adopted from article by Brodoff and according to the authors it has transcultural validity. In our country the solution is only modified by socioeconomic dependence of the adolescent and young adult on the nuclear family. Therefore the separation of the healthy sibling takes frequently an inopportune course and should be adjusted by psychological psychiatric intervention within primary prevention. In the conclusion the authors inform on the psychosomatic reaction of mothers after the establishment of the diagnosis of schizophrenia. A total of seven mothers, sick adolescent (four times a son, three times a daughter). In all instances severe prolonged metrorrhagia was involved. According to catamnestic data four times hysterectomy was performed (always without a pathological finding).