Phenotypical and genotypical characteristics of paired isolates of Pasteurella multocida from the lungs and kidneys of slaughtered pigs. 1990

J Buttenschøn, and S Rosendal
Institute of Hygiene and Microbiology, Royal Veterinary and Agricultural University, Denmark.

Twenty-eight strains of Pasteurella multocida were isolated from 12 Danish and two Canadian abattoir pigs. Fourteen strains were isolated from pulmonary inflammatory lesions, and 14 strains were isolated from kidneys of the same animals. Phenotypical and genotypical characteristics of the strains were evaluated with a view to determine if P. multocida isolated from kidneys might have been disseminated from the lungs. All field strains were capsular type A. The biochemical reactivity in the API-20E and API-ZYM commercial test-kits was uniform with the exception of alpha-glucosidase activity which was present at low levels in only ten of the strains. One strain was markedly serum sensitive, six strains slightly sensitive and the remaining were serum resistant. The peptide patterns obtained by polyacrylamide gel electrophoresis of whole cell proteins of the strains were very uniform with the exception of differences in intensity of bands in the 38 and 34 kD regions. The pattern of oligonucleotides obtained after electrophoresis of total genomic DNA digested with BamHI showed that the paired isolates had identical patterns in eight of the 14 animals. It is therefore likely that isolates from kidney lesions represent blood borne dissemination from primary pulmonary lesions.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D010325 Pasteurella The oldest recognized genus of the family PASTEURELLACEAE. It consists of several species. Its organisms occur most frequently as coccobacillus or rod-shaped and are gram-negative, nonmotile, facultative anaerobes. Species of this genus are found in both animals and humans.
D010326 Pasteurella Infections Infections with bacteria of the genus PASTEURELLA. Pasteurellosis,Infections, Pasteurella,Infection, Pasteurella,Pasteurella Infection,Pasteurelloses
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D004269 DNA, Bacterial Deoxyribonucleic acid that makes up the genetic material of bacteria. Bacterial DNA
D004591 Electrophoresis, Polyacrylamide Gel Electrophoresis in which a polyacrylamide gel is used as the diffusion medium. Polyacrylamide Gel Electrophoresis,SDS-PAGE,Sodium Dodecyl Sulfate-PAGE,Gel Electrophoresis, Polyacrylamide,SDS PAGE,Sodium Dodecyl Sulfate PAGE,Sodium Dodecyl Sulfate-PAGEs
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D000003 Abattoirs Places where animals are slaughtered and dressed for market. Slaughterhouses,Slaughter House,Slaughter Houses,Abattoir,House, Slaughter,Houses, Slaughter,Slaughterhouse

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