BIOMAT Database Logo BIOMAT Database Logo

The serological response of young dogs to the Flury LEP strain of rabies virus vaccine. 1990

H O Aghomo, and O O Oduye, and C E Rupprecht
Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania 19104.

The serological response of puppies from Nigeria to live Flury low egg passage (LEP) rabies vaccine was determined. Two sets of puppies were used: one set from rabies-vaccinated bitches and another set from non-vaccinated bitches. Puppies were vaccinated intramuscularly with Flury LEP strain rabies vaccine and serially bled from the 4th week to the 30th week. Serum rabies virus neutralizing antibodies (VNA) were measured by a modified rapid fluorescent focus inhibition test (RFFIT). Puppies from non-vaccinated bitches responded well to vaccination after the 4th week and through to the 10th week of age, showing a progressive increase in VNA. In contrast, puppies from vaccinated bitches responded well to rabies vaccination only at 10 weeks of age, although detectable maternal rabies VNA and rabies anti-ribonucleoprotein (RNP) antibodies had decreased by 6 weeks post partum.

UI MeSH Term Description Entries
D007112 Immunity, Maternally-Acquired Resistance to a disease-causing agent induced by the introduction of maternal immunity into the fetus by transplacental transfer or into the neonate through colostrum and milk. Fetal Immunity, Maternally-Acquired,Maternally-Acquired Immunity,Neonatal Immunity, Maternally-Acquired,Immunity, Maternally Acquired,Fetal Immunities, Maternally-Acquired,Fetal Immunity, Maternally Acquired,Immunity, Maternally-Acquired Fetal,Immunity, Maternally-Acquired Neonatal,Maternally Acquired Immunities,Maternally Acquired Immunity,Maternally-Acquired Fetal Immunities,Maternally-Acquired Fetal Immunity,Maternally-Acquired Immunities,Maternally-Acquired Neonatal Immunities,Maternally-Acquired Neonatal Immunity,Neonatal Immunities, Maternally-Acquired,Neonatal Immunity, Maternally Acquired
D007117 Immunization, Secondary Any immunization following a primary immunization and involving exposure to the same or a closely related antigen. Immunization, Booster,Revaccination,Secondary Immunization,Booster Immunization,Booster Immunizations,Immunizations, Booster,Immunizations, Secondary,Revaccinations,Secondary Immunizations
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011818 Rabies Acute VIRAL CNS INFECTION affecting mammals, including humans. It is caused by RABIES VIRUS and usually spread by contamination with virus-laden saliva of bites inflicted by rabid animals. Important animal vectors include the dog, cat, bat, fox, raccoon, skunk, and wolf. Encephalitic Rabies,Furious Rabies,Hydrophobia,Paralytic Rabies,Lyssa,Furious Raby,Lyssas,Rabies, Encephalitic,Rabies, Furious,Raby, Furious
D011819 Rabies Vaccines Vaccines or candidate vaccines used to prevent and treat RABIES. The inactivated virus vaccine is used for preexposure immunization to persons at high risk of exposure, and in conjunction with rabies immunoglobulin, for postexposure prophylaxis. Rabies Human Diploid Cell Vaccine,Rabies Vaccine,Vaccine, Rabies,Vaccines, Rabies
D011820 Rabies virus The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates. Rabies viruses
D004283 Dog Diseases Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used. Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D005260 Female Females
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age

Related Publications

H O Aghomo, and O O Oduye, and C E Rupprecht
[Fluorescence serological demonstration of rabies virus strain Flury-LEP in the brain. II. Experiments on dogs].
January 1970, Berliner und Munchener tierarztliche Wochenschrift,
H O Aghomo, and O O Oduye, and C E Rupprecht
TISSUE-CULTURE RABIES VACCINE (FLURY LEP) IN DOGS.
January 1965, American journal of veterinary research,
H O Aghomo, and O O Oduye, and C E Rupprecht
[On the detectability of rabies virus strain FLURY-LEP in the brain of vaccinated dogs].
April 1967, Berliner und Munchener tierarztliche Wochenschrift,
H O Aghomo, and O O Oduye, and C E Rupprecht
[Experiments in dogs vaccinated against rabies with virulin a freeze dried modified live vaccine made from rabies virus strain flury lep].
January 1968, Berliner und Munchener tierarztliche Wochenschrift,
H O Aghomo, and O O Oduye, and C E Rupprecht
[Fluorescent-serological detection of the rabies virus strain Flury-LEP in the brain. I. Studies in guinea pigs].
November 1969, Berliner und Munchener tierarztliche Wochenschrift,
H O Aghomo, and O O Oduye, and C E Rupprecht
Inactivated rabies vaccine produced from the Flury LEP strain of virus grown in BHK-21 suspension cells.
December 1973, Applied microbiology,
H O Aghomo, and O O Oduye, and C E Rupprecht
[Flury strain of rabies virus].
January 1954, Maroc medical,
H O Aghomo, and O O Oduye, and C E Rupprecht
Proceedings: Adaptation of rabies virus (Flury LEP strain) to hamster kidney cell culture. Preliminary report.
January 1974, Acta microbiologica Polonica. Series A: Microbiologia generalis,
H O Aghomo, and O O Oduye, and C E Rupprecht
[Rabies in dogs experimentally infected with street virus and immunized with Flury LEP virus thereafter (author's transl)].
December 1973, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
H O Aghomo, and O O Oduye, and C E Rupprecht
[Titration of rabies vaccine produced with the Flury strain].
May 1959, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale,
Copied contents to your clipboard!