-transparent.png){kind=logo}
OBJECTIVE Adult anorexia nervosa (AN) is associated with inefficient cognitive flexibility and set-shifting. Whether such inefficiencies also characterize adolescent AN is an important area of research. METHODS Adolescents with AN and matched controls were administered a computerized task that required initial learning of an explicit rule using corrective feedback and learning of a new rule after a set number of trials. Adult patients with AN and controls were also examined. RESULTS Adolescents with AN did not differ from matched controls with respect to set-shifting cost (decrease in performance after rule change), whereas adults with AN had significantly greater set-shifting cost compared with controls. CONCLUSIONS This study suggests that set-shifting inefficiencies may not be a vulnerability factor for AN development in adolescents with AN, but might become an important aspect of the disorder at later age, and could point towards developmental neurobiologic brain changes that could affect AN at different ages.
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
May 2006,
Journal of the International Neuropsychological Society : JINS,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
November 2012,
The International journal of eating disorders,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
June 2010,
Annals of general psychiatry,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
November 2014,
Psychiatry research,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
December 2005,
The American journal of psychiatry,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
March 2022,
Eating and weight disorders : EWD,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
December 2012,
Psychiatry research,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
December 2002,
Eating and weight disorders : EWD,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
July 2011,
The Journal of adolescent health : official publication of the Society for Adolescent Medicine,
Megan E Shott, and
J Vincent Filoteo, and
Kelly A C Bhatnagar, and
Nicole J Peak, and
Jennifer O Hagman, and
Roxanne Rockwell, and
Walter H Kaye, and
Guido K W Frank
October 2010,
Journal of psychiatric research,
