Biomaterial Database

[African tick bite fever--rickettsiosis after holiday in South Africa]. 2012

B T Schleenvoigt, and P Keller, and A Stallmach, and M W Pletz

Abteilung für Gastroenterologie, Hepatologie und Infektiologie, Klinik für Innere Medizin II, Universitätsklinikum Jena/Friedrich-Schiller-Universität Jena, Jena, Germany.

METHODS A 61-year-old female patient presented with multiple tick bites. Some of them turned into skin ulcera. The patient acquired the tick bites during a stay in South Africa for several weeks. EXAMINATIONS AND DIAGNOSIS: According to the history and typical skin manifestations, a tick borne infection (rickettsiosis) was diagnosed and serologically confirmed. METHODS The empiric treatment with doxycycline resulted in a fast regression of the skin ulcera. CONCLUSIONS Rickettsial infections can be diagnosed in the presence of typical skin manifestations (eschar andor centripedal exanthema) and after an appropriate history of travel. In such cases, empiric treatment with tetracyclines can be performed.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D001733	Bites and Stings	Injuries inflicted by the TEETH or poisoning caused by VENOMS of animals.	Stings,Bites,Stings and Bites,Bite,Sting
D001907	Boutonneuse Fever	A febrile disease of the Mediterranean area, the Crimea, Africa, and India, caused by infection with RICKETTSIA CONORII.	Mediterranean Spotted Fever,Rickettsia conorii Infection,Boutonneuse Fevers,Fever, Boutonneuse,Fevers, Boutonneuse,Infection, Rickettsia conorii,Infections, Rickettsia conorii,Rickettsia conorii Infections,Spotted Fever, Mediterranean
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260	Female		Females
D005335	Fever of Unknown Origin	Fever in which the etiology cannot be ascertained.	Unknown Origin Fever,Unknown Origin Fevers
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013019	South Africa	A republic in southern Africa, the southernmost part of Africa. It has three capitals: Pretoria (administrative), Cape Town (legislative), and Bloemfontein (judicial). Officially the Republic of South Africa since 1960, it was called the Union of South Africa 1910-1960.	Republic of South Africa,Union of South Africa
D013987	Ticks	Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)	Ixodida,Ixodidas,Tick