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A high blood flow of 400 ml/min induces leukocytosis after 2 hr of dialysis with leukocyte concentrations of 110-150% of predialysis values. The leukocytosis occurs with both low and high biocompatible membranes, such as Cuprophan, Hemophan, and Polyamide. Cuprophan induces the most profound leukopenia, and also induces the most pronounced leukocytosis. For treatments with a given membrane there was, however, no correlation between leukopenia and leukocytosis. Leukopenia was independent of blood flow, while leukocytosis was strongly influenced by this factor. These observations indicate that different factors cause leukopenia and leukocytosis. Although a larger area induced more leukopenia, the effect was small. Membrane area had no effect on leukocytosis. There were no acute clinical side effects during dialysis that could be related to the leukocyte overshoot. The cause and chronic clinical consequences of leukocyte overshoot are unknown.
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
September 1998,
The International journal of artificial organs,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
January 2012,
Journal of nephrology,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
May 1989,
The International journal of artificial organs,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
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C M Kjellstrand
December 2000,
American journal of kidney diseases : the official journal of the National Kidney Foundation,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
March 1984,
British heart journal,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
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C M Kjellstrand
June 1996,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
January 1998,
The Turkish journal of pediatrics,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
May 2010,
Microcirculation (New York, N.Y. : 1994),
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
June 2019,
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners,
P Kjellstrand, and
S H Jacobson, and
R Skröder, and
B Holmquist, and
U Boberg, and
L E Lins, and
P Okmark, and
C M Kjellstrand
March 1973,
Blood,
