Effects of repeated administration of hCG on follicular and luteal characteristics and serum progesterone concentrations in eCG-superovulated Sanjabi ewes. 2012

Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
Department of Animal Science, Faculty of Agriculture, Razi University, Kermanshah 74155, Iran. hkaramishabankareh@yahoo.com

The objective of this study was to evaluate if treatment of equine chorionic gonadotrophin (eCG)-superovulated Sanjabi ewes with repeated administration of human chorionic gonadotropin (hCG) would increase the number of normal corpus luteum (CL) and serum progesterone concentrations and decrease the number of persistent follicles. The superovulated ewes were divided into four groups on day 0 (day of sponge removal); the ewes were treated by an intramuscular administration of 500 IU hCG on day 0 (Group I: n = 10), on days 0 and 1 (Group II: n = 10), or on days 0, 1, and 2 (Group III: n = 10) and no treatment for control group (n = 10). Blood samples were collected on days 0, 1, 2, 5, and 8 (day of slaughter), and serum progesterone concentrations were determined. According to progesterone concentrations, 50 (4/8) and 0 % of the ewes underwent premature luteal regression in the control group and the hCG groups, respectively. There were more CLs in Group III than in Group II and the control group. Ewes treated with hCG had a greater number of normal-looking CL. CL diameter was significantly greater in Group II and Group III than other groups. Total CL weight was significantly (P < 0.05) higher in Group III than in Group I and the control group. Number of persistent follicle and persistent follicle diameter were lower in control group compared to the other groups. Eight days after sponge removal, serum progesterone concentration was significantly higher in Group III than in Group I and the control group. The present results indicate that repeated administration of hCG supported CL formation, increased serum progesterone concentration, and prevented premature luteal regression in eCG-superovulated Sanjabi ewes.

UI MeSH Term Description Entries
D007492 Iran A country bordering the Gulf of Oman, the Persian Gulf, and the Caspian Sea, between Iraq and Pakistan. The capital is Tehran. Islamic Republic of Iran
D011374 Progesterone The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS. Pregnenedione,Progesterone, (13 alpha,17 alpha)-(+-)-Isomer,Progesterone, (17 alpha)-Isomer,Progesterone, (9 beta,10 alpha)-Isomer
D003338 Corpus Luteum The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE. Corpora Lutea,Lutea, Corpora
D003341 Luteolysis Degradation of CORPUS LUTEUM. In the absence of pregnancy and diminishing trophic hormones, the corpus luteum undergoes luteolysis which is characterized by the involution and cessation of its endocrine function. Corpus Luteum Regression,Luteal Regression,Regression, Corpus Luteum,Regression, Luteal
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004797 Enzyme-Linked Immunosorbent Assay An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D005260 Female Females
D006063 Chorionic Gonadotropin A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN). Chorionic Gonadotropin, Human,HCG (Human Chorionic Gonadotropin),Biogonadil,Choriogonadotropin,Choriogonin,Chorulon,Gonabion,Human Chorionic Gonadotropin,Pregnyl,Gonadotropin, Chorionic,Gonadotropin, Human Chorionic
D006064 Gonadotropins, Equine Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies. Pregnant Mare Serum Gonadotropins,PMS Gonadotropins,PMSG (Gonadotropins),Equine Gonadotropins,Gonadotropins, PMS
D006080 Ovarian Follicle An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS. Graafian Follicle,Atretic Follicle,Ovarian Follicles,Atretic Follicles,Follicle, Atretic,Follicle, Graafian,Follicle, Ovarian,Follicles, Atretic,Follicles, Graafian,Follicles, Ovarian,Graafian Follicles

Related Publications

Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
December 2022, Animal reproduction science,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
June 2010, Reproduction in domestic animals = Zuchthygiene,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
July 2023, Animal reproduction science,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
January 1996, Domestic animal endocrinology,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
November 1998, Theriogenology,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
September 1987, Journal of reproduction and fertility,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
February 2004, Reproductive biomedicine online,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
April 1989, Theriogenology,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
January 2004, Theriogenology,
Hamed Karami Shabankareh, and Seyed Behnam Seyedhashemi, and Mehran Torki, and Hamidreza Kelidari, and Alireza Abdolmohammadi
August 2018, Animal reproduction,
Copied contents to your clipboard!