Biomaterial Database

[Measurements of corneal thickness in patients with keratoconjunctivitis sicca]. 1990

O P van Bijsterveld, and J Baardman

Koninklijk Nederlands Gasthuis voor Ooglijders Utrecht.

The average corneal thickness in a group of patients with KCS did not differ significantly from that in a control group. Within the patient group the corneal thickness decreased with decreasing lysozyme concentrations and also with decreasing Schirmer values, but the correlation was weak in both cases. The average central corneal thickness with severe and very severe KCS was greater than that of patients with mild KCS and the control groups. The average corneal thickness in patients with mild KCS was less than that of the control group, but not significantly so. Because of the comparatively small number of patients with severe KCS, an all over increase in corneal thickness in patients with KCS could not be demonstrated.

UI	MeSH Term	Description	Entries
D007638	Keratoconjunctivitis Sicca	Drying and inflammation of the conjunctiva as a result of insufficient lacrimal secretion. When found in association with XEROSTOMIA and polyarthritis, it is called SJOGREN'S SYNDROME.	Sicca, Keratoconjunctivitis
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009113	Muramidase	A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17.	Lysozyme,Leftose,N-Acetylmuramide Glycanhydrolase,Glycanhydrolase, N-Acetylmuramide,N Acetylmuramide Glycanhydrolase
D003315	Cornea	The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)	Corneas
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013666	Tears	The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.	Meibomian Lipids,Meibum,Lipid, Meibomian,Meibomian Lipid,Tear