Carcinosarcoma of the nasal cavity and paranasal sinuses. 1990

M L Shindo, and R B Stanley, and M T Kiyabu
Department of Otolaryngology-Head & Neck Surgery, University of Southern California, Los Angeles.

Malignant neoplasms consisting of an epithelial element and 1 or more nesenchymal components are variously termed teratocarcinosarcoma, carcinosarcoma, malignant teratoma, spindle cell carcinoma, and pseudosarcomatous squamous cell carcinoma. Carcinosarcoma, consisting of a malignant epithelial element and a single malignant mesenchymal component, is extremely rare in the sinonasal tract. We report a case of carcinosarcoma involving the nasal cavity, paranasal sinuses, and anterior cranial fossa. Rapid growth and extensive local destruction are prominent features of this tumor, emphasizing the need for early diagnosis and prompt institution of aggressive therapy. The clinical presentation, pathologic features, and clinical course are detailed.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009296 Nasal Cavity The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA. Nasal Cavities,Cavities, Nasal,Cavity, Nasal
D009669 Nose Neoplasms Tumors or cancer of the NOSE. Cancer of Nose,Nasal Neoplasms,Nose Cancer,Cancer of the Nose,Nasal Cancer,Neoplasms, Nose,Cancer, Nasal,Cancer, Nose,Cancers, Nasal,Cancers, Nose,Nasal Cancers,Nasal Neoplasm,Neoplasm, Nasal,Neoplasm, Nose,Neoplasms, Nasal,Nose Cancers,Nose Neoplasm
D010255 Paranasal Sinus Neoplasms Tumors or cancer of the PARANASAL SINUSES. Cancer of Paranasal Sinus,Neoplasms, Paranasal Sinus,Paranasal Sinus Cancer,Cancer, Paranasal Sinus,Cancers, Paranasal Sinus,Neoplasm, Paranasal Sinus,Paranasal Sinus Cancers,Paranasal Sinus Neoplasm
D002296 Carcinosarcoma A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed) Carcinosarcomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012888 Skull Neoplasms Neoplasms of the bony part of the skull. Neoplasms, Skull,Neoplasm, Skull,Skull Neoplasm

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