Biology and clinical relevance of human natural killer cells.
1990
M J Robertson, and
J Ritz
Division of Tumor Immunology, Dana-Farber Cancer Institute, Boston, MA 02115.
UI
MeSH Term
Description
Entries
D007167
Immunotherapy
Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.
Immunotherapies
D007694
Killer Cells, Natural
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.