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Risk of underdiagnosing amebic dysentery due to false-negative Entamoeba histolytica antigen detection. 2012

Núria Prim, and Pilar Escamilla, and Roser Solé, and Teresa Llovet, and Germán Soriano, and Carmen Muñoz
Servei de Microbiologia, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.

Entamoeba histolytica antigen assays on stool are widely used to diagnose amebiasis. We report a case of confirmed amebic colitis with a false-negative antigen detection that became positive after treatment. Our results indicate that these assays may underdiagnose acute amebic infection when used alone and should be used cautiously.

UI MeSH Term Description Entries
D008297 Male Males
D008853 Microscopy The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe. Compound Microscopy,Hand-Held Microscopy,Light Microscopy,Optical Microscopy,Simple Microscopy,Hand Held Microscopy,Microscopy, Compound,Microscopy, Hand-Held,Microscopy, Light,Microscopy, Optical,Microscopy, Simple
D003951 Diagnostic Errors Incorrect or incomplete diagnoses following clinical or technical diagnostic procedures. Diagnostic Blind Spots,Errors, Diagnostic,Misdiagnosis,Blind Spot, Diagnostic,Blind Spots, Diagnostic,Diagnostic Blind Spot,Diagnostic Error,Error, Diagnostic,Misdiagnoses
D004404 Dysentery, Amebic DYSENTERY caused by intestinal amebic infection, chiefly with ENTAMOEBA HISTOLYTICA. This condition may be associated with amebic infection of the LIVER and other distant sites. Amebiasis, Intestinal,Amebic Dysentery,Colitis, Amebic,Entamoebiasis, Intestinal,Intestinal Amebiasis,Amoebiasis, Intestinal,Amoebic Colitis,Amoebic Dysentery,Intestinal Amoebiasis,Intestinal Entamoeba histolytica Infection,Amebiases, Intestinal,Amebic Colitides,Amebic Colitis,Amebic Dysenteries,Amoebiases, Intestinal,Amoebic Colitides,Amoebic Dysenteries,Colitides, Amebic,Colitides, Amoebic,Colitis, Amoebic,Dysenteries, Amebic,Dysenteries, Amoebic,Dysentery, Amoebic,Entamoebiases, Intestinal,Intestinal Amebiases,Intestinal Amoebiases,Intestinal Entamoebiases,Intestinal Entamoebiasis
D004748 Entamoeba histolytica A species of parasitic protozoa causing ENTAMOEBIASIS and amebic dysentery (DYSENTERY, AMEBIC). Characteristics include a single nucleus containing a small central karyosome and peripheral chromatin that is finely and regularly beaded. Endamoeba histolytica,histolytica, Endamoeba
D005243 Feces Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000953 Antigens, Protozoan Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered. Protozoan Antigens

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