Biomaterial Database

[Healing and integration of ePTFE membranes]. 1990

C Noppe, and H C Wachtel, and J P Bernimoulin, and K Ebert-Kayser

Polikliniken Nord für Zahn-, Mund- und Kieferheilkunde, Freie Universität Berlin.

In this study 40 patients with adult periodontitis received periodontal therapy with ePTFE membranes according to the principle of guided tissue regeneration. Membranes were subgingivally implanted for a period of 4 to 6 weeks. The tissue response was examined clinically and, in 7 cases, also histologically. After removal of the membranes, the membranes themselves and biopsies of the underlying regenerated tissue were prepared for light- and transmission electron microscopy. Clinically most cases showed membrane exposure with recessions and gingival pockets between membrane and gingiva. Histologically all exposed parts of the membranes were contaminated by microorganisms. In the superficial layers of the biopsies microorganisms were found between neutrophils, degenerated collagen fibrils and necrotic cell components.

UI	MeSH Term	Description	Entries
D008567	Membranes, Artificial	Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.	Artificial Membranes,Artificial Membrane,Membrane, Artificial
D008854	Microscopy, Electron	Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.	Electron Microscopy
D010510	Periodontal Diseases	Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.	Parodontosis,Pyorrhea Alveolaris,Disease, Periodontal,Diseases, Periodontal,Parodontoses,Periodontal Disease
D010513	Periodontal Ligament	The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).	Alveolodental Ligament,Alveolodental Membrane,Gomphosis,Alveolodental Ligaments,Alveolodental Membranes,Gomphoses,Ligament, Alveolodental,Ligament, Periodontal,Membrane, Alveolodental,Periodontal Ligaments
D012038	Regeneration	The physiological renewal, repair, or replacement of tissue.	Endogenous Regeneration,Regeneration, Endogenous,Regenerations
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D004846	Epithelial Attachment	A wedge-shaped collar of epithelial cells which form the attachment of the gingiva to the tooth surface at the base of the gingival crevice.	Epithelium, Junctional,Junctional Epithelium,Attachment, Epithelial,Attachments, Epithelial,Epithelial Attachments
D005888	Gingival Pocket	An abnormal extension of a gingival sulcus not accompanied by the apical migration of the epithelial attachment.	Pocket, Gingival,Gingival Pockets,Pockets, Gingival
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man