BIOMAT Database Logo BIOMAT Database Logo

Regional cerebral blood flow study with 99mTc-hexamethyl-propyleneamine oxime single photon emission computed tomography in Alzheimer's and multi-infarct dementia. 1990

L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Department of Neurology, University of Padua Medical School, Italy.

Thirty-four demented patients, 19 with Alzheimer's and 15 with multi-infarct dementia, were studied using single photon emission computed tomography, and 99mTc-hexamethyl-propylenemine oxime as a tracer of regional cerebral perfusion. Tracer activity ratios, determined in cortical and subcortical regions, were compared with those of 11 age-matched controls. In both groups of demented patients, most of the cortical regions showed significant declines in tracer uptake from control values, with the greatest reductions in the parietal cortex. Significantly lower parietal indexes were found in the Alzheimer's patient group as compared both to the control values and to the group of multi-infarct dementia patients. A positive correlation was found between the magnitude of the parietal deficits and the severity of dementia.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009483 Neuropsychological Tests Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D010091 Oximes Compounds that contain the radical R2C Aldoximes,Hydroxyimino Compounds,Ketoxime,Ketoximes,Oxime,Compounds, Hydroxyimino
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002540 Cerebral Cortex The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulci. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions. Allocortex,Archipallium,Cortex Cerebri,Cortical Plate,Paleocortex,Periallocortex,Allocortices,Archipalliums,Cerebral Cortices,Cortex Cerebrus,Cortex, Cerebral,Cortical Plates,Paleocortices,Periallocortices,Plate, Cortical
D004292 Dominance, Cerebral Dominance of one cerebral hemisphere over the other in cerebral functions. Cerebral Dominance,Hemispheric Specialization,Dominances, Cerebral,Specialization, Hemispheric
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
[Single photon emission computed tomograph using 99mTc-hexamethyl-propyleneamine oxime in spinocerebellar degeneration].
March 1988, Kaku igaku. The Japanese journal of nuclear medicine,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Diagnostic role of 99mTc hexamethyl-propyleneamine oxime brain single photon emission computed tomography in Sydenham's chorea.
August 2004, Pediatrics international : official journal of the Japan Pediatric Society,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
[Single photon emission computed tomography (SPECT) using 99mTc-hexamethyl propyleneamine oxime in patients with ischemic cerebral diseases: comparative study of N-isopropyl-p-[123I]-iodoamphetamine and 99mTc-DTPA SPECT].
July 1989, Kaku igaku. The Japanese journal of nuclear medicine,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Reduced Regional Cerebral Blood Flow Measured by 99mTc-Hexamethyl Propylene Amine Oxime Single-Photon Emission Computed Tomography in Microgravity Simulated by 5-Day Dry Immersion.
January 2021, Frontiers in physiology,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Increased regional cerebral perfusion by 99mTc hexamethyl propylene amine oxime single photon emission computed tomography in post-traumatic stress disorder.
June 2000, Military medicine,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Acutely administered haloperidol-induced widespread reduction of regional cerebral blood flow observed from subtraction of brain imaging with single photon emission computed tomography using technetium-99m hexamethyl-propyleneamine oxime.
January 1990, Neuropsychobiology,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography.
March 1997, Biological psychiatry,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
[Single photon emission computed tomography by using N-isopropyl-p-[123I]-iodoamphetamine and 99mTc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].
February 1989, Kaku igaku. The Japanese journal of nuclear medicine,
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Single photon emission computed tomography with 99mTc hexamethyl propylene amine oxime (HMPAO) and focal motor seizures.
January 1994, Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985),
L Battistin, and G Pizzolato, and M Dam, and I Ponza, and N Borsato, and P L Zanco, and G Ferlin
Acutely administered haloperidol-induced pattern changes of regional cerebral blood flow in schizophrenics. Observation from subtraction of brain imaging with single photon emission computed tomography using technetium-99m hexamethyl-propyleneamine oxime.
January 1992, Neuropsychobiology,
Copied contents to your clipboard!