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[Possibilities and limitations of heterotopic auxiliary liver transplantation]. 1990
D Baumgartner, and
O T Terpstra, and
E J Hesselink, and
T H Groenland, and
S W Schalm, and
W Weimar, and
F W ten Kate, and
J Stibbe, and
C B Reuvers, and
J L Terpstra
Departemente Chirurgie, Universitätsspital, Dijkzigt, Erasmus-Universität, Rotterdam, Niederlande.
Although auxiliary heterotopic liver transplantation offers theoretical advantages over orthotopic liver replacement, clinical results have heretofore been dismal. After development of a technique of reduced size liver grafts provided with portal and arterial blood and venous drainage via the suprahepatic V. cava (HLT) in experimental animals, this method was applied in 21 transplantations in 19 patients. 11 of 16 patients with chronic liver insufficiency and one of three patients with fulminant liver failure survived transplantation for at least 1 year. HLT was well tolerated even by high-risk patients. Possibilities and limitations of this novel approach are discussed.
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