-transparent.png){kind=logo}
Screening of antibiotics preferentially active against ras oncogene-expressed cells. 1990
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
Showa College of Pharmaceutical Sciences, Machida city, Tokyo, Japan.
During the course of in vitro screening of agents which are preferentially active against ras oncogene-expressed cells, a new anthracycline (identified as 2-demethylsteffimycin D) and a heptaene (possibly a new member of partricins) were isolated from microbial fermentation broths. Among known compounds tested, 5-fluorouracil, 5-fluorodeoxyuridine and oxanosine showed high selectivity towards ras oncogene-expressed cells.
Related Publications
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
September 1993,
Biological & pharmaceutical bulletin,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
November 1985,
Molecular and cellular biology,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
March 1959,
Applied microbiology,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
December 1988,
American journal of obstetrics and gynecology,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
April 1994,
Biological & pharmaceutical bulletin,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
July 1987,
Molecular and cellular biology,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
January 1979,
Transplantation,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
April 2004,
Archives of microbiology,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
August 1997,
Brain research. Molecular brain research,
K Suzukake-Tsuchiya, and
Y Moriya, and
K Yamazaki, and
M Hori, and
N Hosokawa, and
T Sawa, and
H Iinuma, and
H Naganawa, and
C Imada, and
M Hamada
November 1987,
British journal of cancer,
