BIOMAT Database Logo BIOMAT Database Logo

Paternal occupation and birth defects: findings from the National Birth Defects Prevention Study. 2012

Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
North Carolina Center for Birth Defects Research and Prevention, Gillings School of Global Public Health, Department of Epidemiology, CB#7435, University of North Carolina, Chapel Hill, NC 27599, USA. ta_desrosiers@unc.edu

OBJECTIVE Several epidemiological studies have suggested that certain paternal occupations may be associated with an increased prevalence of birth defects in offspring. Using data from the National Birth Defects Prevention Study, the authors investigated the association between paternal occupation and birth defects in a case-control study of cases comprising over 60 different types of birth defects (n=9998) and non-malformed controls (n=4066) with dates of delivery between 1997 and 2004. METHODS Using paternal occupational histories reported by mothers via telephone interview, jobs were systematically classified into 63 groups based on shared exposure profiles within occupation and industry. Data were analysed using bayesian logistic regression with a hierarchical prior for dependent shrinkage to stabilise estimation with sparse data. RESULTS Several occupations were associated with an increased prevalence of various birth defect categories, including mathematical, physical and computer scientists; artists; photographers and photo processors; food service workers; landscapers and groundskeepers; hairdressers and cosmetologists; office and administrative support workers; sawmill workers; petroleum and gas workers; chemical workers; printers; material moving equipment operators; and motor vehicle operators. CONCLUSIONS Findings from this study might be used to identify specific occupations worthy of further investigation and to generate hypotheses about chemical or physical exposures common to such occupations.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007407 Interviews as Topic Works about conversations with an individual or individuals held in order to obtain information about their background and other personal biographical data, their attitudes and opinions, etc. It includes works about school admission or job interviews. Group Interviews,Interviewers,Interviews, Telephone,Oral History as Topic,Group Interview,Interview, Group,Interview, Telephone,Interviewer,Interviews, Group,Telephone Interview,Telephone Interviews
D008297 Male Males
D009790 Occupations Crafts, trades, professions, or other means of earning a living. Vocations,Occupation,Vocation
D005220 Fathers Male parents, human or animal. Father
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000013 Congenital Abnormalities Malformations of organs or body parts during development in utero. Birth Defects,Congenital Defects,Deformities,Fetal Anomalies,Fetal Malformations,Abnormalities, Congenital,Defects, Congenital,Abnormality, Congenital,Anomaly, Fetal,Birth Defect,Congenital Abnormality,Congenital Defect,Defect, Birth,Defect, Congenital,Deformity,Fetal Anomaly,Fetal Malformation,Malformation, Fetal
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001499 Bayes Theorem A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result. Bayesian Analysis,Bayesian Estimation,Bayesian Forecast,Bayesian Method,Bayesian Prediction,Analysis, Bayesian,Bayesian Approach,Approach, Bayesian,Approachs, Bayesian,Bayesian Approachs,Estimation, Bayesian,Forecast, Bayesian,Method, Bayesian,Prediction, Bayesian,Theorem, Bayes
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor

Related Publications

Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Birth defects associated with paternal firefighting in the National Birth Defects Prevention Study.
January 2023, American journal of industrial medicine,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Maternal occupation and the risk of birth defects: an overview from the National Birth Defects Prevention Study.
January 2010, Occupational and environmental medicine,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Maternal occupation and the risk of major birth defects: a follow-up analysis from the National Birth Defects Prevention Study.
June 2013, International journal of hygiene and environmental health,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Maternal nutrition and gastroschisis: findings from the National Birth Defects Prevention Study.
May 2011, American journal of obstetrics and gynecology,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Acetaminophen use in pregnancy and risk of birth defects: findings from the National Birth Defects Prevention Study.
January 2010, Obstetrics and gynecology,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Findings from the National Birth Defects Prevention Study: Interpretation and translation for the clinician.
August 2015, Birth defects research. Part A, Clinical and molecular teratology,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Paternal occupation and risk of birth defects in offspring.
November 1995, Epidemiology (Cambridge, Mass.),
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
The National Birth Defects Prevention Study.
January 2001, Public health reports (Washington, D.C. : 1974),
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Maternal occupation as a nail technician or hairdresser during pregnancy and birth defects, National Birth Defects Prevention Study, 1997-2011.
January 2022, Occupational and environmental medicine,
Tania A Desrosiers, and Amy H Herring, and Stuart K Shapira, and Mariëtte Hooiveld, and Tom J Luben, and Michele L Herdt-Losavio, and Shao Lin, and Andrew F Olshan, and
Fluconazole use and birth defects in the National Birth Defects Prevention Study.
May 2016, American journal of obstetrics and gynecology,
Copied contents to your clipboard!