Evidence of non-maternally mediated acceleration of eye-opening in 'enriched' artificially reared rat pups. 1990

J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
Department of Child Health, University of Manchester, U.K.

Rat pups were artificially reared, without their mothers, from postnatal day 5. They were exposed thereafter to impoverished or enriched environmental conditions. The enrichment included gentling, social interaction and homing experience. Enriched rats showed accelerated eye-opening compared with their impoverished littermates (P less than 0.02). This is the first demonstration of stimulation-induced acceleration of development which cannot have been maternally mediated.

UI MeSH Term Description Entries
D008297 Male Males
D008426 Maternal Deprivation Prolonged separation of the offspring from the mother. Deprivation, Maternal,Deprivations, Maternal,Maternal Deprivations
D010812 Physical Stimulation Act of eliciting a response from a person or organism through physical contact. Stimulation, Physical,Physical Stimulations,Stimulations, Physical
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D005123 Eye The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light. Eyes
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012931 Social Environment The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community. Social Context,Environment, Social,Social Ecology,Context, Social,Contexts, Social,Ecologies, Social,Ecology, Social,Environments, Social,Social Contexts,Social Ecologies,Social Environments
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
September 2000, Physiology & behavior,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
July 1986, Brain research,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
January 1977, Biology of the neonate,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
December 1987, The American journal of physiology,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
December 1983, Brain research bulletin,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
December 1990, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
January 1984, Alcohol (Fayetteville, N.Y.),
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
March 1994, Developmental psychobiology,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
September 1994, The Journal of nutrition,
J L Smart, and A C McMahon, and R F Massey, and G N Akbar, and M A Warren
November 1998, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology,
Copied contents to your clipboard!