Melanotic neuroectodermal tumour of infancy. 2010

Sweta Pattanayak Mohanty, and Jay Gopal Ray, and Richa, and Sanjit Mukherjee, and Chitra Mandal, and Keya Chaudhuri
Department of Oral Pathology, Dr R Ahmed Dental College and Hospital, Kolkata, India.

Melanotic neuroectodermal tumour of infancy (MNTI) is a rare benign tumour of neural crest origin that was first described by Krompecher in 1918.1 It is predominantly found in infancy, with about 92% of cases below the age of 12 months and 82% below the age of 6 months. The predominant site of origin is in the premaxilla though it is reported at other sites also including the skull, the mandible, the epididymis and the brain.2 The lesions often have areas of bluish discolouration on the surface and are characterised by displacement of the involved tooth bud and local aggressiveness. The present report deals with two cases of MNTI, a 5-month-old baby girl and a 6-month-old baby boy who reported to the Department of Oral and Maxillofacial Pathology, Dr R Ahmed Dental College and Hospital, Kolkata, India. The clinical, radiological, histological and immunohistochemical findings, confirmed the diagnosis of MNTI. Flow cytometry was performed to analyse aneuploidy. The tumours were treated surgically with no history of recurrence to date.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D008437 Maxilla One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS. Maxillae,Maxillary Bone,Bone, Maxillary,Bones, Maxillary,Maxillary Bones,Maxillas
D008441 Maxillary Neoplasms Cancer or tumors of the MAXILLA or upper jaw. Maxillary Neoplasm,Neoplasm, Maxillary,Neoplasms, Maxillary
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D017600 Neuroectodermal Tumor, Melanotic A benign, rapidly growing, deeply pigmented tumor of the jaw and occasionally of other sites, consisting of an infiltrating mass of cells arranged in an alveolar pattern, and occurring almost exclusively in infants. Its source of origin is in dispute, the various theories giving rise to its several names. (Dorland, 27th ed) Melanoameloblastoma,Progonoma, Melanotic,Retinal Anlage Tumor,Anlage Tumor, Retinal,Anlage Tumors, Retinal,Melanoameloblastomas,Melanotic Neuroectodermal Tumor,Melanotic Neuroectodermal Tumors,Melanotic Progonoma,Melanotic Progonomas,Neuroectodermal Tumors, Melanotic,Progonomas, Melanotic,Retinal Anlage Tumors,Tumor, Melanotic Neuroectodermal,Tumor, Retinal Anlage,Tumors, Melanotic Neuroectodermal,Tumors, Retinal Anlage

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