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Highly regioselective synthesis of aryl chalcogenides through C-H functionalization of arenes. 2012

Jun-Hao Cheng, and Chih-Lun Yi, and Tsung-Jui Liu, and Chin-Fa Lee
Department of Chemistry, National Chung Hsing University, Taichung, 402, Taiwan, ROC.

We report here the regioselective synthesis of aryl chalcogenides through the iridium-catalyzed meta C-H borylation followed by copper-catalyzed C-S coupling reaction with chalcogenide sources in one pot, giving the 3,5-disubstituted aryl chalcogenides with high regioselectivity and good yields.

UI MeSH Term Description Entries
D007495 Iridium A metallic element with the atomic symbol Ir, atomic number 77, and atomic weight 192.22.
D002384 Catalysis The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction. Catalyses
D013237 Stereoisomerism The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D018011 Chalcogens The elements OXYGEN; POLONIUM; SELENIUM; SULFUR; and TELLURIUM; that form group 16 (formerly group VI) of the periodic table. Group 16 Elements,Elements, Group 16

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