Biomaterial Database

[Oncogenic transformation by the tax gene of HTLV-I]. 1990

M Hatanaka

Institute for Virus Research, Kyoto University.

UI	MeSH Term	Description	Entries
D002460	Cell Line	Established cell cultures that have the potential to propagate indefinitely.	Cell Lines,Line, Cell,Lines, Cell
D002471	Cell Transformation, Neoplastic	Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.	Neoplastic Transformation, Cell,Neoplastic Cell Transformation,Transformation, Neoplastic Cell,Tumorigenic Transformation,Cell Neoplastic Transformation,Cell Neoplastic Transformations,Cell Transformations, Neoplastic,Neoplastic Cell Transformations,Neoplastic Transformations, Cell,Transformation, Cell Neoplastic,Transformation, Tumorigenic,Transformations, Cell Neoplastic,Transformations, Neoplastic Cell,Transformations, Tumorigenic,Tumorigenic Transformations
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014162	Transfection	The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.	Transfections
D015368	Human T-lymphotropic virus 1	A strain of PRIMATE T-LYMPHOTROPIC VIRUS 1 isolated from mature T4 cells in patients with T-lymphoproliferation malignancies. It causes adult T-cell leukemia (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED), T-cell lymphoma (LYMPHOMA, T-CELL), and is involved in mycosis fungoides, SEZARY SYNDROME and tropical spastic paraparesis (PARAPARESIS, TROPICAL SPASTIC).	ATLV,Adult T-Cell Leukemia-Lymphoma Virus I,HTLV-1,HTLV-I,Human T-Cell Leukemia Virus I,Leukemia Virus I, Human T-Cell,T-Cell Leukemia Virus I, Human,Adult T Cell Leukemia Lymphoma Virus I,Human T Cell Leukemia Virus I,Leukemia Lymphoma Virus I, Adult T Cell,Leukemia Virus I, Human T Cell,T Cell Leukemia Virus I, Human,Human T lymphotropic virus 1
D015967	Gene Expression Regulation, Viral	Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses.	Regulation of Gene Expression, Viral,Viral Gene Expression Regulation,Regulation, Gene Expression, Viral
D016355	Genes, pX	DNA sequences that form the coding region for at least three proteins which regulate the expression of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The proteins are p21(x), p27(rex), and p40(tax). The tax (trans-activator x) and rex (regulator x) genes are part of pX but are in overlapping reading frames. X was the original designation for the sequences or region (at that time of unknown function) in the long open reading frame (lor) which is now called pX.	Genes, rex,Genes, tax,HTLV-I rex Genes,HTLV-I tax Genes,HTLV-II rex Genes,HTLV-II tax Genes,pX Genes,rex Genes,tax Genes,Genes, lor,Gene, HTLV-I rex,Gene, HTLV-I tax,Gene, HTLV-II rex,Gene, HTLV-II tax,Gene, lor,Gene, pX,Gene, rex,Gene, tax,Genes, HTLV-I rex,Genes, HTLV-I tax,Genes, HTLV-II rex,Genes, HTLV-II tax,HTLV I rex Genes,HTLV I tax Genes,HTLV II rex Genes,HTLV II tax Genes,HTLV-I rex Gene,HTLV-I tax Gene,HTLV-II rex Gene,HTLV-II tax Gene,lor Gene,lor Genes,pX Gene,rex Gene,rex Gene, HTLV-I,rex Gene, HTLV-II,rex Genes, HTLV-I,rex Genes, HTLV-II,tax Gene,tax Gene, HTLV-I,tax Gene, HTLV-II,tax Genes, HTLV-I,tax Genes, HTLV-II
D016356	Gene Products, tax	Transcriptional trans-acting proteins of the promoter elements found in the long terminal repeats (LTR) of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The tax (trans-activator x; x is undefined) proteins act by binding to enhancer elements in the LTR.	Trans-Activator Protein p40(tax),Trans-Activator Protein p40(x),p40(tax),tax Gene Products,tax Protein,Gene Product, tax,Trans-Activator Protein p40(lor),Trans-Activator Protein p40x,Trans-Activator Protein pX,Transactivator Protein p40(x),Transactivator p40(tax),Transforming Antigen p40x,p40 tax,Antigen p40x, Transforming,Trans Activator Protein p40x,Trans Activator Protein pX,p40x, Trans-Activator Protein,p40x, Transforming Antigen,pX, Trans-Activator Protein,tax Gene Product
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus