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The constriction-dilation cycles of pupils exposed to a stationary, discrete slit-lamp beam were significantly prolonged in 25 myasthenic patients (1,060.4 +/- 45.8 msec) undergoing therapy with steroids, anticholinesterases, or both, compared to normal controls (801.9 +/- 8.6 msec) or subjects receiving steroids for nonneurological disease (860.9 +/- 14.9 msec). The duration of myasthenia correlated with the slowing of the cycle time. Myasthenia gravis may affect ectodermally derived smooth muscle or the autonomic neuromuscular junction or both, and not be restricted to the well-demonstrated alterations of neuromuscular junction in striated muscle of mesodermal origin. Alternatively, prolonged pupillary cycles could be attributed to dysfunction of central pathways of the pupillary light reflex.
F E Lepore, and
G E Sanborn, and
J T Slevin
January 1971,
Shinkei kenkyu no shimpo. Advances in neurological sciences,
F E Lepore, and
G E Sanborn, and
J T Slevin
January 1982,
Transactions of the ophthalmological societies of the United Kingdom,
F E Lepore, and
G E Sanborn, and
J T Slevin
January 1995,
Eye (London, England),
F E Lepore, and
G E Sanborn, and
J T Slevin
September 1990,
The International journal of neuroscience,
F E Lepore, and
G E Sanborn, and
J T Slevin
December 1994,
Clinics in chest medicine,
F E Lepore, and
G E Sanborn, and
J T Slevin
August 1976,
The British journal of ophthalmology,
F E Lepore, and
G E Sanborn, and
J T Slevin
March 1961,
Neurology,
F E Lepore, and
G E Sanborn, and
J T Slevin
March 1980,
Annals of neurology,
F E Lepore, and
G E Sanborn, and
J T Slevin
January 2012,
PloS one,
F E Lepore, and
G E Sanborn, and
J T Slevin
March 2012,
Revue neurologique,
