Biomaterial Database

Correlation between haptoglobin and sialic acid or mucoprotein in diseased bovine serum. 1990

S Makimura, and M Usui

Department of Veterinary Medicine, Faculty of Agriculture, Miyazaki University, Japan.

The correlation between haptoglobin (Hp) and mucoprotein or sialic acid in sera from diseased cattle was examined to evaluate the clinical application of serum Hp. First, the ranges of mucoprotein, sialic acid and hemoglobin binding capacity (HbBC) of 46 healthy cattle were determined. Then, levels of these reactants in 35 cattle suffering from various diseases were measured. The frequency of the abnormal values was 94.3% in mucoprotein, 45.7% in sialic acid and 82.9% in HbBC in diseased cattle. There was a significant correlation between mucoprotein and sialic acid, and between HbBC and mucoprotein or sialic acid. Some correlation between mucoprotein and neutrophils or alpha-globulin was also observed. In spite of high levels of mucoprotein and sialic acid, lower HbBC than expected levels were often observed in inflammatory disorders. Such cases might be complicated with some hemolytic disorders such as piroplasmosis. Determining serum HbBC together with other acute phase reactants might be useful for evaluating inflammatory diseases complicated with hemolytic disorders.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009088	Mucoproteins	Conjugated proteins in which mucopolysaccharides are combined with proteins. The mucopolysaccharide moiety is the predominant group with the protein making up only a small percentage of the total weight.
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418	Cattle Diseases	Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.	Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D005260	Female		Females
D006242	Haptoglobins	Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.	Haptoglobin
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012794	Sialic Acids	A group of naturally occurring N-and O-acyl derivatives of the deoxyamino sugar neuraminic acid. They are ubiquitously distributed in many tissues.	N-Acetylneuraminic Acids,Acids, N-Acetylneuraminic,Acids, Sialic,N Acetylneuraminic Acids