BIOMAT Database Logo BIOMAT Database Logo

Acute graft versus host disease after orthotopic liver transplantation. 2012

Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
University of Zagreb School of Medicine, University Hospital Merkur, Zagreb, Croatia.

Graft versus host disease (GVHD) is an uncommon complication after orthotopic liver transplantation (OLT) with an incidence of 0.1-2%, but an 80-100% mortality rate. Patients can present with skin rashes, diarrhea, and bone marrow aplasia between two to eight weeks after OLT. Diagnosis of GVHD is made based on clinical and histologic evidence, supported by chimerism studies showing donor HLA alleles in the recipient bone marrow or blood. Several therapeutic approaches have been used for the management of GVHD after OLT including increased immunosuppression, decreased immunosuppression, and cellular therapies. However, success rates have been low, and new approaches are needed.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D005260 Female Females
D006086 Graft vs Host Disease The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. Graft-Versus-Host Disease,Homologous Wasting Disease,Runt Disease,Graft-vs-Host Disease,Disease, Graft-Versus-Host,Disease, Graft-vs-Host,Disease, Homologous Wasting,Disease, Runt,Diseases, Graft-Versus-Host,Diseases, Graft-vs-Host,Graft Versus Host Disease,Graft-Versus-Host Diseases,Graft-vs-Host Diseases
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D016031 Liver Transplantation The transference of a part of or an entire liver from one human or animal to another. Grafting, Liver,Hepatic Transplantation,Liver Transplant,Transplantation, Hepatic,Transplantation, Liver,Hepatic Transplantations,Liver Grafting,Liver Transplantations,Liver Transplants,Transplant, Liver

Related Publications

Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Acute graft-versus-host disease after liver transplantation.
February 2007, Transplantation,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-versus-host disease after orthotopic liver transplantation in a child.
October 1990, Transplantation proceedings,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-versus-host disease, a rare complication after orthotopic liver transplantation.
January 2018, Clinical case reports,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Fatal graft-versus-host-disease: a grave complication after orthotopic liver transplantation.
December 1994, Transplantation proceedings,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Rash as the first manifestation of acute graft-versus-host disease after orthotopic liver transplantation.
January 2011, European journal of dermatology : EJD,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Acute Graft-Versus-Host Disease After Orthotopic Liver Transplantation: Predicting This Rare Complication Using Machine Learning.
March 2022, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-versus-host disease after orthotopic liver transplantation: multivariate analysis of risk factors.
December 2015, Clinical transplantation,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-versus-host disease after liver transplantation.
January 2011, Clinics (Sao Paulo, Brazil),
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-versus-host disease after liver transplantation.
August 1993, Journal of the American Academy of Dermatology,
Inga Mandac Rogulj, and Joachim Deeg, and Stephanie J Lee
Graft-Versus-Host Disease After Liver Transplantation.
February 2020, Clinical liver disease,
Copied contents to your clipboard!