Biomaterial Database

Burkitt's lymphoma in Ethiopian children. 1990

E Daniel

Department of Pediatrics and Child Health, Faculty of Medicine, Addis Ababa University, Ethiopia.

Burkitt's lymphoma is the commonest malignancy seen in childhood in Ethiopia. Thirty-nine children admitted to the Ethio-Swedish Children's Hospital from January 1971 to December 1988 were studied. The male to female ratio was 1.3:1, 24(63%) were from non-malarious areas, 29(76%) came from areas with altitude above 1500 meters above sea level, 36(95%) came from areas with mean annual temperature above 16 degrees C and 35(61%) patients came from areas with mean annual rainfall above 1000 mm. The commonest presentation was abdominal mass followed by jaw swelling. Eight (20%) patients died in hospital. The geographic distribution of the tumour seems to be different from that seen in some parts of Africa. Studies with regard to Epstein-Barr virus linkage in Ethiopia are warranted.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002051	Burkitt Lymphoma	A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.	African Lymphoma,Burkitt Cell Leukemia,Burkitt Tumor,Lymphoma, Burkitt,Burkitt Leukemia,Burkitt's Leukemia,Burkitt's Lymphoma,Burkitt's Tumor,Leukemia, Lymphoblastic, Burkitt-Type,Leukemia, Lymphocytic, L3,Lymphocytic Leukemia, L3,Burkitts Leukemia,Burkitts Lymphoma,Burkitts Tumor,L3 Lymphocytic Leukemia,L3 Lymphocytic Leukemias,Leukemia, Burkitt,Leukemia, Burkitt Cell,Leukemia, Burkitt's,Leukemia, L3 Lymphocytic,Lymphoma, African,Lymphoma, Burkitt's,Tumor, Burkitt,Tumor, Burkitt's
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D002980	Climate	The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Climates
D005002	Ethiopia	An independent state in eastern Africa. Ethiopia is located in the Horn of Africa and is bordered on the north and northeast by Eritrea, on the east by Djibouti and Somalia, on the south by Kenya, and on the west and southwest by Sudan. Its capital is Addis Ababa.	Federal Democratic Republic of Ethiopia
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006813	Humidity	A measure of the amount of WATER VAPOR in the air.	Humidities
D000531	Altitude	A vertical distance measured from a known level on the surface of a planet or other celestial body.	Altitudes