-transparent.png){kind=logo}
The effects of two fat-modified diets, one rich in polyunsaturated and the other in oleic acids, were studied in 10 healthy young males with regard to bile lipid composition, plasma lipids and lipoproteins. The two experimental diets were given for 2 weeks each and findings compared with those from the subject's normal diet. The fat-modified diets had marked but comparable effects on plasma total cholesterol (decreases by 23% and 16% respectively), on LDL-cholesterol (decreases by 27% and 17% respectively) and on HDL-cholesterol (decreases by 26% and 27% respectively). HDL apolipoproteins A-I and A-II were unaffected. Therefore, the apo A-I/HDL-cholesterol and apo A-II/HDL-cholesterol ratios significantly increased. The "lithogenic index" as a measure for the relationship of cholesterol to bile acids and phospholipids, and thus for the solubility of cholesterol in gallbladder bile, was not affected by the lipid lowering diets, which therefore should not increase the risk of cholelithiasis.
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
September 1982,
Die Medizinische Welt,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
January 1969,
The Journal of clinical investigation,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
February 1982,
Atherosclerosis,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
May 1987,
Journal of lipid research,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
May 2000,
The Journal of nutritional biochemistry,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
December 2002,
Acta cardiologica,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
August 1984,
Clinical pharmacology and therapeutics,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
April 1992,
Clinical chemistry,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
January 1981,
Clinical cardiology,
G Schlierf, and
T Nikolaus, and
A Stiehl, and
C C Heuck, and
G Middelhoff, and
W Riesen, and
P Oster
May 1968,
Metabolism: clinical and experimental,
