BIOMAT Database Logo BIOMAT Database Logo

A new flavanocoumarin from the root of Flemingia philippinensis. 2013

Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
Guangdong Open Access Laboratory of Agricultural Product Processing, Sericulture and Farm Produce Processing Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, PR China.

One new flavanocoumarin, flemicoumarin A (1) was isolated from the EtOAc-soluble partition of the root of Flemingia philippinensis, along with three known compounds, namely 4,2'-epoxy-4',5-dihydroxy-7,5'-dimethoxy-3-phenylcoumarin (2), kaempferol 6-C-glucoside (3) and dracocephaloside (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR, CD and MS data. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Compounds 1-4 exhibited inactivity against MCF-7, A549 and Hep-G2 human cancer cell lines in vitro by MTT colorimetric assay.

UI MeSH Term Description Entries
D007887 Fabaceae The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of "beans" belong to this family. Afzelia,Amorpha,Andira,Baptisia,Callerya,Ceratonia,Clathrotropis,Colophospermum,Copaifera,Delonix,Euchresta,Guibourtia,Legumes,Machaerium,Pithecolobium,Stryphnodendron,Leguminosae,Pea Family,Pithecellobium,Tachigalia,Families, Pea,Family, Pea,Legume,Pea Families
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D010936 Plant Extracts Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard. Herbal Medicines,Plant Extract,Extract, Plant,Extracts, Plant,Medicines, Herbal
D002942 Circular Dichroism A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Circular Dichroism, Vibrational,Dichroism, Circular,Vibrational Circular Dichroism
D003374 Coumarins Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. 1,2-Benzopyrone Derivatives,1,2-Benzopyrones,Coumarin Derivative,Coumarine,1,2-Benzo-Pyrones,Benzopyran-2-ones,Coumarin Derivatives,Coumarines,1,2 Benzo Pyrones,1,2 Benzopyrone Derivatives,1,2 Benzopyrones,Benzopyran 2 ones,Derivative, Coumarin,Derivatives, 1,2-Benzopyrone,Derivatives, Coumarin
D000431 Ethanol A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. Alcohol, Ethyl,Absolute Alcohol,Grain Alcohol,Alcohol, Absolute,Alcohol, Grain,Ethyl Alcohol
D013058 Mass Spectrometry An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers. Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D018517 Plant Roots The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990) Plant Bulbs,Plant Root,Bulb, Plant,Bulbs, Plant,Plant Bulb,Root, Plant,Roots, Plant

Related Publications

Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
A new coumestan with immunosuppressive activities from Flemingia philippinensis.
June 2011, Fitoterapia,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
Prenylated isoflavones from Flemingia philippinensis.
December 2008, Magnetic resonance in chemistry : MRC,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
A new benzofuran derivative from Flemingia philippinensis Merr. et Rolfe.
June 2012, Molecules (Basel, Switzerland),
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
[Flavonoids from roots of Flemingia philippinensis].
March 2009, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
[Pharmacognostical identification of Flemingia philippinensis].
May 1984, Zhong yao tong bao (Beijing, China : 1981),
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
Xanthine Oxidase Inhibition and Anti-LDL Oxidation by Prenylated Isoflavones from Flemingia philippinensis Root.
July 2020, Molecules (Basel, Switzerland),
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
[Effect of PP333 treatment on seed yield and root of Flemingia philippinensis].
August 2012, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
[Studies on the chemical constituents of Flemingia philippinensis].
January 1991, Yao xue xue bao = Acta pharmaceutica Sinica,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
Competitive neutrophil elastase inhibitory isoflavones from the roots of Flemingia philippinensis.
August 2018, Bioorganic chemistry,
Manqin Fu, and Dun Deng, and Riming Huang, and Nenling Zhang, and Zhiwei Su, and Samuel X Qiu
Highly potent bacterial neuraminidase inhibitors, chromenone derivatives from Flemingia philippinensis.
May 2019, International journal of biological macromolecules,
Copied contents to your clipboard!