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The kinetics of ultraviolet inactivation for two human rhinoviruses and poliovirus were compared. No major differences in the rates of ultraviolet inactivation were detectable. All viral preparations inactivated by ultraviolet irradiation induced neutralizing antibody in guinea pigs. In contrast, when guinea pigs were immunized with a heat inactivated rhinovirus preparation, little or no neutralizing antibody was elicited. Immune electron microscopy of the heated rhinovirus preparations revealed the presence of particles resembling empty capsids. These results suggest that rhinoviruses and enteroviruses are affected in a similar manner when subjected to ultraviolet or heat inactivation.
J H Hughes, and
M Mitchell, and
V V Hamparian
July 2022,
Water research,
J H Hughes, and
M Mitchell, and
V V Hamparian
February 1970,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J H Hughes, and
M Mitchell, and
V V Hamparian
January 1966,
Biofizika,
J H Hughes, and
M Mitchell, and
V V Hamparian
January 1966,
Biofizika,
J H Hughes, and
M Mitchell, and
V V Hamparian
October 2010,
International journal of food microbiology,
J H Hughes, and
M Mitchell, and
V V Hamparian
August 2012,
Water research,
J H Hughes, and
M Mitchell, and
V V Hamparian
October 2021,
Water research,
J H Hughes, and
M Mitchell, and
V V Hamparian
January 1954,
Acta physiologica Polonica,
J H Hughes, and
M Mitchell, and
V V Hamparian
October 1982,
Infection and immunity,
J H Hughes, and
M Mitchell, and
V V Hamparian
January 2015,
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering,
