BIOMAT Database Logo BIOMAT Database Logo

Quantitation of emphysema by computed tomography using a "density mask" program and correlation with pulmonary function tests. 1990

M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Division of Respiratory Medicine, University of British Columbia, Vancouver General Hospital, Canada.

We used a CT program "density mask" outlining areas with attenuation values less than -910 HU, to indicate areas of emphysema on a chest CT and to provide an overall percentage of lung involvement by emphysema. The "density mask" quantitation of emphysema was previously shown to correlate well with the pathologic assessment of emphysema in patients undergoing lung resection. We compared the CT quantitation of emphysema with mean lung density, overall lung volume on CT and pulmonary function tests in 85 patients. There was a significant correlation between the extent of emphysema on CT and FEV/FVC percent of predicted, functional residual capacity percent predicted and Dsb percent predicted. Determination of the percentage of lung with areas of low attenuation by CT provides a useful method for quantitating emphysema in life and correlates significantly with pulmonary function tests.

UI MeSH Term Description Entries
D008176 Lung Volume Measurements Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle. Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011656 Pulmonary Emphysema Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions. Emphysema, Pulmonary,Centriacinar Emphysema,Centrilobular Emphysema,Emphysemas, Pulmonary,Focal Emphysema,Panacinar Emphysema,Panlobular Emphysema,Pulmonary Emphysemas,Centriacinar Emphysemas,Centrilobular Emphysemas,Emphysema, Centriacinar,Emphysema, Centrilobular,Emphysema, Focal,Emphysema, Panacinar,Emphysema, Panlobular,Emphysemas, Centriacinar,Emphysemas, Centrilobular,Emphysemas, Focal,Emphysemas, Panacinar,Emphysemas, Panlobular,Focal Emphysemas,Panacinar Emphysemas,Panlobular Emphysemas
D011856 Radiographic Image Enhancement Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed. Digital Radiography,Image Enhancement, Radiographic,Radiography, Digital,Enhancement, Radiographic Image,Enhancements, Radiographic Image,Image Enhancements, Radiographic,Radiographic Image Enhancements
D012044 Regression Analysis Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable. Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Detection of emphysema with computed tomography. Correlation with pulmonary function tests and chest radiography.
April 1988, Investigative radiology,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
[Pulmonary emphysema: quantification using computed tomography and correlations with respiratory function tests].
January 1993, Revue des maladies respiratoires,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
[Correlation of grading of pulmonary emphysema by computed tomography to pulmonary function].
February 1988, Nihon Kyobu Shikkan Gakkai zasshi,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
"Density mask". An objective method to quantitate emphysema using computed tomography.
October 1988, Chest,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Pulmonary function tests versus computed tomography in sheep with experimental emphysema.
June 2005, Experimental lung research,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests.
January 2019, Pulmonary medicine,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Texture-based quantification of pulmonary emphysema on high-resolution computed tomography: comparison with density-based quantification and correlation with pulmonary function test.
June 2008, Investigative radiology,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
[Longitudinal follow-up evaluation of pulmonary emphysema using high-resolution Computed Tomography (HRCT) study and pulmonary function tests].
September 2001, La Radiologia medica,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
Chronic pulmonary thromboembolism. Air trapping on computed tomography and correlation with pulmonary function tests.
January 2003, Journal of computer assisted tomography,
M Kinsella, and N L Müller, and R T Abboud, and N J Morrison, and A DyBuncio
[Quantitative assessment of pulmonary emphysema with computerized tomography. Comparison of the visual score and high resolution computerized tomography, expiratory density mask with spiral computerized tomography and respiratory function tests].
April 1997, La Radiologia medica,
Copied contents to your clipboard!